BACKGROUND Existing literature on anti-oxidant capacity of ginseng has been inconsistent due to variance in the profile of ginseng steroids (Ginsenosides) that is because of differences in seasons and species. METHODS We used various doses of ginseng steroids to determine its effect on oxidative stress and anti-oxidant capacity of rat skeletal muscle against exercise. RESULTS Under non-exer...

Korean ginseng (Panax ginseng C.A. Meyer) has been widely used for medicinal purposes and contains potent plant secondary metabolites, including ginsenosides. To obtain transcriptomic data that offers a more comprehensive view of functional genomics in P. ginseng, we generated genome-wide transcriptome data from four different P. ginseng tissues using PacBio isoform sequencing (Iso-Seq) technol...

Ginseng, Panax ginseng C. A. Meyer, is an industrial crop in China and Korea. The functional components in ginseng roots and rhizomes are characteristic ginsenosides. This work developed a new high-performance liquid chromatography coupled with electrospray ionization ion trap time-of-flight multistage mass spectrometry (LC-ESI-IT-TOF-MS(n)) method to identify the triterpenoids. Sixty compounds...

UNLABELLED BACKGROUND With the gaining popularity of commercially prepared decoctions of herbal medicines on the market, an objective and efficient way to reveal the authenticity of such products is urgently needed. Previous attempts to use chromatographic or spectroscopic methods to identify ginseng samples made use of components derived from methanol extracts of the herb. It was not establ...

Background: With the gaining popularity of commercially prepared decoctions of herbal medicines on the market, an objective and efficient way to reveal the authenticity of such products is urgently needed. Previous attempts to use chromatographic or spectroscopic methods to identify ginseng samples made use of components derived from methanol extracts of the herb. It was not established that th...

AimsThere is an increasing awareness of the importance root-associated bacteria and fungi to plant growth. At present, little known about whether different ginseng cultivars affect soil rhizosphere microbial community. Here, we examined changes in microorganismal diversity composition rhizospheres cultivars.MethodsThe four cultivars, namely CBGL (GAOLI ginseng), JYSH (COMMON ginseng) SZSZ (SHIZ...

Ginseng is one of the most widely used Chinese herbal medicines. In this report, the relatively short-term effect of ginseng extract on the immunoglobulin production and cytokine production was studied. The ginseng extract was prepared by boiling the ground ginseng root in 50% ethanol. The specific pathogen-free mice were intraperitoneally (i.p.) injected with various doses of ginseng extract f...

Although new antidiabetic agents are introduced, alternative medicine with natural compounds such as ginseng offer a potential benefit, as they have a wide margin of safety with no no side-effects. Following informed consent patients with type 2 diabetes (oral medication 80%, insulin therapy 20%) were randomly assigned to receive an extract of Siberian (480 mg/day; n = 27) American (Panax) gins...

Panax ginseng is the most commonly used ginseng in the diet and medicine in many Asian countries especially in China. It is categorized as an 'adaptogen' that helps to adapt against higher levels of stress and maintains a good health. In general, animal toxicity studies found that Panax ginseng is very safe with no teratogenicity or mutagenicity. However, data on the effect of Panax ginseng sup...

Ginseng, Panax ginseng C.A. Meyer, is one of the most important medicinal plants for human health and medicine. It has been documented that over 80% of genes conferring resistance to bacteria, viruses, fungi and nematodes are contributed by the nucleotide binding site (NBS)-encoding gene family. Therefore, identification and characterization of NBS genes expressed in ginseng are paramount to it...