The ribosomal RNA (rRNA) genes in Giardia lamblia are present as short tandem arrays of a 5.6 Kb repeat unit on at least six telomeres. Four of these telomeres have the same overall organisation comprising a domain ranging in size from 25 to 300 Kb, delineated chromosome internally by a conserved island of restriction enzyme sites. Cloned lines of G. lamblia derived from the WB strain contain p...

The microaerophilic parasite Giardia lamblia is a causative agent of dysentery affecting hundreds of millions of people around the globe every year. The symptoms of the disease, commonly referred to as giardiasis, are diarrhea, nausea, and malabsorption. Treatment of giardiasis is exclusively based on chemotherapy with antigiardial drugs, including metronidazole, albendazole, and nitazoxanide. ...

Background: We wanted to investigate the relationship between intestinal parasitic infection and anaemic patients. Methods: stool samples were examined for Protozoa and Helminths infection by routine microscopy and blood samples were performed using the electronic cell counter Coulter. Results: Out of 592 samples 277(46.79%) were positive among them Entamoeba histolytica 80(28%), Ancylostoma du...

BACKGROUND Giardiasis is an intestinal infection correlated with poverty and poor drinking water quality, and treatment options are limited. According to the Center for Disease Control and Prevention, Giardia infections afflict nearly 33% of people in developing countries, and 2% of the adult population in the developed world. This study describes the single cyclic nucleotide-specific phosphodi...

BACKGROUND Infections with helminths and other intestinal parasites are an important but neglected problem in children in developing countries. Accurate surveys of intestinal parasites in children inform empirical treatment regimens and can assess the impact of school based drug treatment programmes. There is limited information on this topic in Cambodia. METHODS In a prospective study of int...

Giardia lamblia is an intestinal protozoan parasite required to survive in the environment in order to be transmitted to a new host. To ensure parasite survival, flagellated trophozoites colonizing the small intestine differentiate into non-motile environmentally-resistant cysts which are then shed in the environment. This cell differentiation process called encystation is characterized by sign...

The filamentous protein giardin is structurally associated with microtubules in Giardia lamblia. We present the sequence of one giardin chain (beta-giardin) corresponding to band 14B of Giardia cytoskeleton proteins (1). A Giardia cDNA library cloned and expressed in lamda gt11 was screened with antibodies monospecific to giardin (2). One positive phage clone (SR7) selected for sequencing conta...