نتایج جستجو برای: gge بای پلات

تعداد نتایج: 4768  

2017
Anna Elisabetta Vaudano Sara Olivotto Andrea Ruggieri Giuliana Gessaroli Valentina De Giorgis Antonia Parmeggiani Pierangelo Veggiotti Stefano Meletti

PURPOSE To provide imaging biomarkers of generalized spike-and-wave discharges (GSWD) in patients with GLUT1 deficiency syndrome (GLUT1DS). METHODS Eighteen GLUT1DS patients with pathogenetic mutation in SLC2A1 gene were studied by means of Video-EEG simultaneously recorded with functional MRI (VideoEEG-fMRI). A control group of sex and age-matched patients affected by Genetic Generalized Epi...

2016
Jerzy P. Szaflarski Seongtaek Lee Jane B. Allendorfer Tyler E. Gaston Robert C. Knowlton Sandipan Pati Lawrence W. Ver Hoef Georg Deutsch

BACKGROUND Genetic generalized epilepsies (GGEs) are associated with microstructural brain abnormalities that can be evaluated with diffusion tensor imaging (DTI). Available studies on GGEs have conflicting results. Our primary goal was to compare the white matter structure in a cohort of patients with video/EEG-confirmed GGEs to healthy controls (HCs). Our secondary goal was to assess the pote...

2017
Felicitas Becker Christopher A. Reid Kerstin Hallmann Han‐Shen Tae A. Marie Phillips Georgeta Teodorescu Yvonne G. Weber Ailing Kleefuss‐Lie Christian Elger Edward Perez‐Reyes Steven Petrou Wolfram S. Kunz Holger Lerche Snezana Maljevic

Objective Genetic generalized epilepsy (GGE) encompasses seizure disorders characterized by spike-and-wave discharges (SWD) originating within thalamo-cortical circuits. Hyperpolarization-activated (HCN) and T-type Ca2+ channels are key modulators of rhythmic activity in these brain regions. Here, we screened HCN4 and CACNA1H genes for potentially contributory variants and provide their functio...

Journal: :Journal of lipid research 1988
C A Vézina R W Milne P K Weech Y L Marcel

The heterogeneity of serum lipoproteins (excluding very low density (VLDL) and intermediate density (IDL) lipoproteins) and that of lipoproteins secreted by HepG2 cells has been studied by immunoblot analysis of the apolipoprotein composition of the particles separated by polyacrylamide gradient gel electrophoresis (GGE) under nondenaturing conditions. The reactions of antibodies to apoA-I, apo...

Journal: :Genetics and molecular research : GMR 2016
A M Corrêa P E Teodoro M C Gonçalves A Santos F E Torres

Recently, the genotype plus genotype x environment interaction (GGE) biplot methodology has been used to investigate genotype x environment interactions in several crop species, but has not been applied to the common bean (Phaseolus vulgaris L.) crop in Brazil. The aim of this study was to identify common bean genotypes that exhibit high grain yield and stability in the State of Mato Grosso do ...

ژورنال: :علوم گیاهان زراعی ایران 2011
امیدعلی اکبرپور حمید دهقانی بهزاد سرخی لله لو

به منظور بررسی پاسخ لاین های مختلف جو به شرایط متفاوت محیطی و تعیین پایداری عملکرد در آنها، بیست لاین امیدبخش جو در قالب طرح پایه بلوک های کامل تصادفی با سه تکرار در هشت ایستگاه تحقیقاتی سرد کشور به مدت دو سال (1387-1385) مورد مطالعه قرار گرفت. از پنج پارامتر پایداری مدل چند متغیره امی و پارامترهای پایداری شوکلا ( ) و بجپای (i) برای معرفی ژنوتیپ های پایدار استفاده شد. از تجزیه به مؤلفه های اصلی...

Journal: :Human molecular genetics 2012
Michael Steffens Costin Leu Ann-Kathrin Ruppert Federico Zara Pasquale Striano Angela Robbiano Giuseppe Capovilla Paolo Tinuper Antonio Gambardella Amedeo Bianchi Angela La Neve Giovanni Crichiutti Carolien G F de Kovel Dorothée Kasteleijn-Nolst Trenité Gerrit-Jan de Haan Dick Lindhout Verena Gaus Bettina Schmitz Dieter Janz Yvonne G Weber Felicitas Becker Holger Lerche Bernhard J Steinhoff Ailing A Kleefuß-Lie Wolfram S Kunz Rainer Surges Christian E Elger Hiltrud Muhle Sarah von Spiczak Philipp Ostertag Ingo Helbig Ulrich Stephani Rikke S Møller Helle Hjalgrim Leanne M Dibbens Susannah Bellows Karen Oliver Saul Mullen Ingrid E Scheffer Samuel F Berkovic Kate V Everett Mark R Gardiner Carla Marini Renzo Guerrini Anna-Elina Lehesjoki Auli Siren Michel Guipponi Alain Malafosse Pierre Thomas Rima Nabbout Stephanie Baulac Eric Leguern Rosa Guerrero Jose M Serratosa Philipp S Reif Felix Rosenow Martina Mörzinger Martha Feucht Fritz Zimprich Claudia Kapser Christoph J Schankin Arvid Suls Katrin Smets Peter De Jonghe Albena Jordanova Hande Caglayan Zuhal Yapici Destina A Yalcin Betul Baykan Nerses Bebek Ugur Ozbek Christian Gieger Heinz-Erich Wichmann Tobias Balschun David Ellinghaus Andre Franke Christian Meesters Tim Becker Thomas F Wienker Anne Hempelmann Herbert Schulz Franz Rüschendorf Markus Leber Steffen M Pauck Holger Trucks Mohammad R Toliat Peter Nürnberg Giuliano Avanzini Bobby P C Koeleman Thomas Sander

Genetic generalized epilepsies (GGEs) have a lifetime prevalence of 0.3% and account for 20-30% of all epilepsies. Despite their high heritability of 80%, the genetic factors predisposing to GGEs remain elusive. To identify susceptibility variants shared across common GGE syndromes, we carried out a two-stage genome-wide association study (GWAS) including 3020 patients with GGEs and 3954 contro...

2014
Rogério Lunezzo de Oliveira Renzo Garcia Von Pinho Daniel Furtado Ferreira Luiz Paulo Miranda Pires Wagner Mateus Costa Melo

This paper proposes an alternative method for evaluating the stability and adaptability of maize hybrids using a genotype-ideotype distance index (GIDI) for selection. Data from seven variables were used, obtained through evaluation of 25 maize hybrids at six sites in southern Brazil. The GIDI was estimated by means of the generalized Mahalanobis distance for each plot of the test. We then proc...

ژورنال: :مجله علوم کشاورزی ایران 2005
جهانبخش سوری حمید دهقانی سید حسین صباغ پور

به منظور ارزیابی تنوع ژنتیکی در نخود و شناسائی ژنوتیپ های مقاوم به خشکی و همچنین تعیین مناسب ترین شاخص مقاومت به خشکی، تعداد 25 ژنوتیپ نخود در قالب طرح بلوک های کامل تصادفی با 4 تکرار در دو شرایط تنش و عدم تنش آبی در مرکز تحقیقات کرمانشاه (سرارود) مورد آزمایش قرار گرفتند. شاخص های کمی مقاومت شامل میانگین حسابی (mp)، میانگین هندسی (gmp)، تحمل به تنش (sti) و شاخص های حساسیت به تنش (ssi) و تحمل (t...

Journal: :Arteriosclerosis 1986
T A Musliner C Giotas R M Krauss

Analysis of human plasma by gradient gel electrophoresis (GGE) revealed multiple distinct bands in the size range between very low density (VLDL) and low density lipoproteins (LDL). GGE of intermediate density lipoproteins (IDL) from normal subjects consistently showed two major bands with particle diameters in the range of 275 to 300 A. The larger, usually predominant subspecies was designated...

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