Some DNA damage-recognition proteins, transcription factors, mismatch repair proteins and DNA polymerases discriminate between cisplatin (CP)and oxaliplatin (OX)-GG DNA adducts, and this is thought to help explain differences in efficacy, toxicity and mutagenicity of CP and OX. In addition, differential recognition of CPand OX-GG adducts by some proteins has been shown to be highly dependent on...
