نتایج جستجو برای: genipin gel

تعداد نتایج: 105470  

The antimicrobial activity of a wound dressing is a key factor for preventing and treating wound infection. The current study evaluated the physiochemical properties and antimicrobial activities of semi-IPNs (interpenetrating polymer networks) based on chitosan/polyvinyl alcohol (PVA) films and nanofibers as candidates for wound dressings and investigated the effects of morphologies (nanofibrou...

2017
Yoshiki Koriyama Yusuke Takagi Kenzo Chiba Matsumi Yamazaki Kayo Sugitani Kunizo Arai Hirokazu Suzuki Satoru Kato

Like other CNS neurons, mature retinal ganglion cells (RGCs) are unable to regenerate their axons after nerve injury due to a diminished intrinsic regenerative capacity. One of the reasons why they lose the capacity for axon regeneration seems to be associated with a dramatic shift in RGCs’ program of gene expression by epigenetic modulation. We recently reported that (1R)-isoPropyloxygenipin (...

Journal: :The spine journal : official journal of the North American Spine Society 2015
Morakot Likhitpanichkul Yesul Kim Olivia M Torre Eugene See Zepur Kazezian Abhay Pandit Andrew C Hecht James C Iatridis

BACKGROUND CONTEXT Intervertebral discs (IVDs) are attractive targets for local drug delivery because they are avascular structures with limited transport. Painful IVDs are in a chronic inflammatory state. Although anti-inflammatories show poor performance in clinical trials, their efficacy treating IVD cells suggests that sustained, local drug delivery directly to painful IVDs may be beneficia...

Journal: :Journal of Biomedical Materials Research Part B: Applied Biomaterials 2018

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