نتایج جستجو برای: genetic covariance

تعداد نتایج: 641415  

Journal: :Investigative ophthalmology & visual science 2011
Samantha J Fahy Cong Sun Gu Zhu Paul R Healey Tim D Spector Nicolas G Martin Paul Mitchell Tien Y Wong David A Mackey Christopher J Hammond Toby Andrew

PURPOSE Retinal arteriolar and venular calibers are highly heritable and associated with cardiovascular disease. This study was designed to investigate the relative influence of genetic and environmental factors on the high phenotypic correlation (r = 0.59) between these two traits and to assess the shared and specific influence of established and novel cardiovascular disease risk factors on th...

Journal: :Genetics 2013
Shizhong Xu

A new mixed-model method was developed for mapping quantitative trait loci (QTL) by incorporating multiple polygenic covariance structures. First, we used genome-wide markers to calculate six different kinship matrices. We then partitioned the total genetic variance into six variance components, one corresponding to each kinship matrix, including the additive, dominance, additive × additive, do...

  Genetic parameters for birth weight and survival traits were estimated using data collected from 1995 to 2009 in Jafarabad Moghani Sheep Breeding Station. Number of observation for survival and birth weight were 7202 and 6585, respectively. Genetic parameters were estimated using restricted maximum likelihood (REML) procedure under 16 different models, including animal, threshold and sire mod...

Journal: :Evolution; international journal of organic evolution 2013
Miguel Prôa Paul O'Higgins Leandro R Monteiro

Studies of evolutionary divergence using quantitative genetic methods are centered on the additive genetic variance-covariance matrix (G) of correlated traits. However, estimating G properly requires large samples and complicated experimental designs. Multivariate tests for neutral evolution commonly replace average G by the pooled phenotypic within-group variance-covariance matrix (W) for evol...

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