The omic technologies have been reviewed extensively elsewhere, and their fundamentals will not be described herein. Suffice it to say that DNA microarrays generate large data sets relevant to gene expression and genetic variation (primarily SNPs [single nucleotide polymorphisms]); mass spectrometry and gel electrophoresis generate smaller, but still extensive, data sets for protein expression;...

– Sustainable evaluation of construction projects in strategy-focused condition is the main issue for municipalities to appropriately improve public sector services. In this respect, the group decision-making methods could help experts to select suitable sustainable projects and to schedule them regarding their ranking results. Therefore, the objective of this study is to present a hybrid group...

A large portion of automated testing techniques has been developed for the statement or branch test coverage criteria. Among structural criteria, however, research on basis path testing has received little attention. The basis path testing requires a set of basis paths to be executed during testing. However, traditional testing methods for basis path generation consider only the control flow of...

We present a simple, yet effective, approach to Semi-Supervised Learning. Our approach is based on estimating density-based distances (DBD) using a shortest path calculation on a graph. These Graph-DBD estimates can then be used in any distancebased supervised learning method, such as Nearest Neighbor methods and SVMs with RBF kernels. In order to apply the method to very large data sets, we al...

BiDaS is a web-application that can generate massive Monte Carlo simulated sequence or numerical feature data sets (e.g. dinucleotide content, composition, transition, distribution properties) based on small user-provided data sets. BiDaS server enables users to analyze their data and generate large amounts of: (i) Simulated DNA/RNA and aminoacid (AA) sequences following practically identical s...

Previous models of cardiac Ca2+ sparks have assumed that Ca2+ currents through the Ca2+ release units (CRUs) were approximately 1-2 pA, producing sparks with peak fluorescence ratio (F/F(0)) of approximately 2.0 and a full-width at half maximum (FWHM) of approximately 1 microm. Here, we present actual Ca2+ sparks with peak F/F(0) of >6 and a FWHM of approximately 2 microm, and a mathematical mo...

in this paper, the important formation control problem of nonholonomic wheeled mobile robots is investigated via a leader-follower strategy. to this end, the dynamics model of the considered wheeled mobile robot is derived using lagrange equations of motion. then, using adams multi-body simulation software, the obtained dynamics of the wheeled system in matlab software is verified. after that, ...

We derive a Markov chain to sample from the posterior distribution for a phylogenetic tree given sequence information from the corresponding set of organisms, a stochastic model for these data, and a prior distribution on the space of trees. A transformation of the tree into a canonical cophenetic matrix form suggests a simple and effective proposal distribution for selecting candidate trees cl...