Gastroesophageal cancers (such as esophageal, gastric and gastroesophageal-junction -GEJ- lesions) are worldwide a leading cause of death being relatively rare but highly aggressive. In the past years, a clear shift in the location of upper gastrointestinal tract tumors has been recorded, both affecting the scientific research and the modern clinical practice. The integration of pre- or peri-op...

The true value of endoscopic ultrasound (EUS) post-neoadjuvant chemotherapy for esophageal carcinoma is not established. Superior loco-regional detail may yield useful staging and prognostic information but information on its accuracy, as compared with computed tomography (CT), remains undefined and limited by small study size. We prospectively studied 109 patients with gastroesophageal cancer;...

introduction: gastroesophageal reflux (ger) is the most common esophageal disorder, which occurs at all ages. ger is defined as the passage of gastric contents into the esophagus. ger disease (gerd), which is a long-term complication, is a common pediatric problem. clinical manifestations of gerd in infants include regurgitation, irritability, choking, gagging, vomiting, poor weight gain, and r...

Gastroesophageal reflux induced cough is a common cause of chronic cough, and proton pump inhibitors are a standard therapy. However, the patients unresponsive to the standard therapy are difficult to treat and remain a challenge to doctors. Here, we summarized the experience of successful resolution of refractory chronic cough due to gastroesophageal reflux with baclofen in three patients. It ...

Gastroesophageal varices are a common complication of cirrhosis and are present in approximately 50% of patients with cirrhosis.[1] Acute gastroesophageal variceal hemorrhage is a severe complication of cirrhosis or portal hypertension associated with high mortality.[1‐3] Although mortality of gastroesophageal variceal hemorrhage has decreased in the past three decades, it remains the most comm...

background: reflux disease is a common gastrointestinal problem. the association between reflux disease and gastritis pattern is controversial. aim : to determine the association between reflux disease and gastritis pattern in patients with helicobacter pylori (h. pylori) infection. methods: 470 patients with dyspepsia and reflux disease were enrolled in this study. the inclusion criteria were ...

gastric varices (gv) are responsible for 10-30% of all variceal  hemorrhage. however, they tend to bleed more severely with higher mortality. around 35-90% rebleed after spontaneous hemostasis. approximately 50% of patients with cirrhosis of liver harbor  gastroesophageal varices. in this review, new treatment modalities in the form of endoscopic treatment options and interventional radiologica...

A 72-year-old man with pancreatic cancer presented coffee-ground emesis for 2 days. Computed tomography of abdomen oral contrast showed gastric distention, transition point at level the bulb and large volume ascites. Endoscopy severe diffuse exudative esophagitis involving most esophagus areas black discoloration mid distal edematous (Figures B). infiltrating mass, consistent known cancer, was ...

Chemotherapy for advanced gastric and gastroesophageal junction carcinomas remains suboptimal. Both irinotecan (Camptosar) and cisplatin (Platinol) are active against this group of malignancies. This article focuses on the results of an ongoing phase II trial with this combination in patients with advanced gastric or gastroesophageal junction carcinoma. Data from this trial suggest that the com...

Background: Esophageal cancer is considered to be a one of the most lethal malignancy. Indian population have seen lot changes in epidemiology this deadly cancer. However very few studies been done from northern India regarding and etiopathogenesis disease. Majority esophageal cancers (about 90%) are either squamous cell or Adenocarcinoma. Any factor that causes chronic irritation inflammation ...