نتایج جستجو برای: galectin 1

تعداد نتایج: 2755360  

Journal: :Clinical chemistry 2012
E Wilson Grandin Petr Jarolim Sabina A Murphy Lea Ritterova Christopher P Cannon Eugene Braunwald David A Morrow

BACKGROUND Galectin-3 is a β-galactoside-binding lectin that has been implicated in cardiac fibrosis and remodeling, is increased in models of failure-prone hearts, and has prognostic value in patients with heart failure (HF). The relationship between galectin-3 and the development of HF after acute coronary syndrome (ACS) is unknown. METHODS In a nested case-control study among patients with...

Journal: :PLoS ONE 2008
Armando Bartolazzi Calogero D'Alessandria Maria Gemma Parisella Alberto Signore Fabrizio Del Prete Luca Lavra Sten Braesch-Andersen Roberto Massari Carlo Trotta Alessandro Soluri Salvatore Sciacchitano Francesco Scopinaro

BACKGROUND The prevalence of thyroid nodules increases with age, average 4-7% for the U.S.A. adult population, but it is much higher (19-67%) when sub-clinical nodules are considered. About 90% of these lesions are benign and a reliable approach to their preoperative characterization is necessary. Unfortunately conventional thyroid scintigraphy does not allow the distinction among benign and ma...

Journal: :Glycobiology 2003
Silvia G Correa Claudia E Sotomayor Maria P Aoki Cristina A Maldonado Gabriel A Rabinovich

Recent evidence has implicated galectins and their carbohydrate ligands as master regulators of the inflammatory response. Galectin-1, a member of this family, has shown specific anti-inflammatory and immunoregulatory effects. To gain insight into the potential mechanisms involved in these effects, we investigated the effects of galectin-1 in L-arginine metabolism of peritoneal rat macrophages....

Journal: :International journal of oncology 2011
Mouldy Sioud Anne Mobergslien Abdellatif Boudabous Yngvar Fløisand

Human galectins are involved in a variety of biological and pathological processes including cell adhesion, apoptosis, differentiation, immune regulation and tumour evasion. Previously, we identified galectin-3 as the first human lectin involved in the modulation of the immunosuppressive potential of mesenchymal stem cells (MSCs). In this study, we report on the expression profiles and potentia...

Journal: :international journal of reproductive biomedicine 0
hossein nikzad hamed haddad kashani maryam kabir-salmani yoshihiro akimoto mitsutoshi iwashita

background: the up-regulation of galectin-3, galectin-9, and galectin-15 expression in the luminal and glandular epithelium was reported in preparation of the endometrium for embryo implantation at the midlutheal phase. however, no data was available regarding the expression and the distribution pattern of galectin-8 in the human endometrium during a regular menstrual cycle. objective: the curr...

2014
ANAËLLE DURAY THIBAULT DE MAESSCHALCK CHRISTINE DECAESTECKER MYRIAM REMMELINK GILBERT CHANTRAIN JENNIFER NEIVEYANS MIHAELA HOROI XAVIER LEROY HANS-JOACHIM GABIUS SVEN SAUSSEZ

Galectins, a family of endogenous lectins, are multifunctional effectors that act at various sites and can be used in immunohistochemical localization studies of diseased states. Since they form a potentially cooperative and antagonistic network, we tested the hypothesis that histopathological fingerprinting of galectins could refine the molecular understanding of naso-sinusal pathologies. Usin...

2017
Yuan Zhou Zhi-heng Chen Bo-hao Lu Hong-gang Jiang

The incidence of Papillary Thyroid Carcinoma (PTC) has increased gradually in recent years, especially for Papillary Thyroid Microcarcinoma (PTMC). The purpose of this study was to evaluate the expression of Ki67, CK19, Galectin-3 and HBME-1 protein in PTMC and evaluate the clinical significance of differential diagnosis. The specimens of 80 PTMC cases and 40 benign papillary hyperplasia thyroi...

2005
M.von Wolff

The emerging functionality of the sugar code via cell surface glycans and endogenous lectins ascribes pertinent roles in cell physiology to the carbohydrate signals of cellular glycoconjugates. To initiate monitoring of endogenous lectins in human endometrium, we focused on a family of growth/adhesion-regulatory lectins, i.e. galectins. Comprehensive fingerprinting was performed on samples thro...

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