In order to discover novel probes that may help in the investigation and control of infectious diseases through a new mechanism of action, we have evaluated a library of phenol-based natural products (NPs) for enzyme inhibition against four recently characterized pathogen β-family carbonic anhydrases (CAs). These include CAs from Mycobacterium tuberculosis, Candida albicans, and Cryptococcus ne...

We describe the development of an epitope-blocking enzyme-linked immunosorbent assay (ELISA) for the sensitive and rapid detection of antibodies to Ross River virus (RRV) in human sera and known vertebrate host species. This ELISA provides an alternative method for the serodiagnosis of RRV infections.

Although we understand the ecological processes eliciting changes in plant community composition during secondary succession, we do not understand whether co-occurring changes in plant detritus shape saprotrophic microbial communities in soil. In this study, we investigated soil microbial composition and function across an old-field chronosequence ranging from 16 to 86 years following agricultu...

The effect of onion and garlic extracts on fungal growth and keratinolytic activity was studied in Trichophyton mentagrophytes as one of the major etiologic agents of human and animal dermatophytosis in Iran and other parts of the world. In order to find out the best keratinase producer for further steps, culture conditions for 30 strains of T. mentagrophytes isolated from human dermatophytosis...

A study was carried out on totally chlorine-free (TCF) bleachability of dimethyl formamide (DMF) treated bagasse pulps exposed to CZ-3 and FP 90031-sp strains of white-rot fungus Ceriporiopsis subvermispora. This process involved an oxygen and peroxide stage bleaching sequence. The effect of enzymatic stage on bleachability properties was studied and compared with control pulps, processed witho...

different compositions of liquid media were used for their efficacy in the production of beta-galactosidase by aspergillus oryzae in submerged fermentation. enzyme production was improved by switching from lactose-based media to soybean meal- and wheat bran-based media. further improvement was made when the soybean meal medium was supplemented with sodium nitrate and magnesium sulfate. results ...

Lignocellulolytic enzymes play an important role in various industrial applications as well the sustainable valorisation of lignocellulosic materials. Enzyme production using fungi has shown great advantages such high enzyme diversity, efficiency, and availability solid waste raw Agricultural waste, abundant non-food competitive feedstock, can be used to produce fungal lignocellulolytic enzymes...

Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanisms of Th2 cell accumulation are multifactorial and incompletely known. To investigate Th2 cell responses to pulmonary fungal infection, we developed a peptide-MHCII tetramer to track antigen-specific CD4+ T cells produced in response to infection with the fungal pathogen Cryptococcus neoformans. W...

Fungus-growing termites rely on mutualistic fungi of the genus Termitomyces and gut microbes for plant biomass degradation. Due to a certain degree of symbiont complementarity, this tripartite symbiosis has evolved as a complex bioreactor, enabling decomposition of nearly any plant polymer, likely contributing to the success of the termites as one of the main plant decomposers in the Old World....

Fibrinolytic proteases operate directly on fibrin clot and are able to maintain blood flow. Fungi show up as viable sources for obtaining this enzyme. The purpose of systematic review is unveil all the information concerning production, purification characterization fibrinolytic by fungi. search was conducted in ScienceDirect, PubMed Scopus databases, using keywords “(Fibrinolytic enzyme) OR (F...