Outcomes in depression treatment research include both changes in symptom severity and functional impairment. Symptom measures tend to be the standard outcome but we argue that there are benefits to considering functional outcomes. An exhaustive literature review shows that the relationship between symptoms and functioning remains unexpectedly weak and often bidirectional. Changes in functionin...

personalized medicine as a novel field of medicine refers to the prescription of specific therapeutics procedure for an individual. this approach has established based on pharmacogenetic and pharmacogenomic information and data. the terms precision and personalized medicines are sometimes applied interchangeably. however, there has been a shift from “personalized medicine” towards “precision me...

objective: neurocognitive deficits are now recognized as part of the fundamental disturbances and are a major determinant of functional outcome in psychosis. a cross-sectional association between cognitive deficits and poor social and occupational outcomes has been demonstrated; and treatment of cognitive impairment at the time of the first episode may have the potential to change functional ou...

the anterior maxilla presents a challenging milieu interior for ideal placement of implants because of the compromised bone quality. with the advent of intraoral bone harvesting and augmentation techniques, immediate implant placement into fresh extraction sockets have become more predictable. immediate implant placement has numerous advantages compared to the delayed procedure including superi...

wound complications following ankle fracture surgery are a major concern. through the use of minimally invasive surgical techniques some of these complications can be mitigated. recent investigations have reported on percutaneous fixation of distal fibula fractures demonstrating similar radiographic and functional outcomes to traditional open approaches. the purpose of this manuscript is to des...

in recent years, numerous approaches have been applied for finding the solutions of functional equations. one of them is the optimal homotopy asymptotic method. in current paper, this method has been applied for obtaining the approximate solution of fisher equation. the reliability of the method will be shown by solving some examples of various kinds and comparing the obtained outcomes with the ...

Statistical process control (SPC) theory takes a negative view of adjustment of process settings, which is termed tampering. In contrast, quality and lean programmes actively encourage operators to acts of intervention and personal agency in the improvement of production outcomes. This creates a conflict that requires operator judgement: How does one differentiate between unnecessary tampering ...

Osteoarthritis of the knee is a debilitating condition affecting increasing numbers of individuals each year. One option for treatment is orthotic knee braces, but a little independent reviews have taken place to date on their relative outcomes for users. This study therefore evaluates the efficacy of different types of knee orthoses (braces) with regard to key aspects of use, including gait pa...

Background:  There is no consensus on the best surgical treatment in Kienböck disease. We compared the shortterm outcomes of radial shortening osteotomy and capitate shortening osteotomy in patients affected with this disease.  Methods:  In a retrospective study of 21 patients with Lichtman stage IIIA of Kienböck disease, 12 patients with an average follow up of 3.2 ± 0.6 years had radial short...