Abstract Chronic kidney disease (CKD) is characterized by clustered age-independent concentric LV geometry, geometry-independent systolic dysfunction, and age heart rate-independent diastolic dysfunction. Concentric geometry always associated with echocardiographic markers of abnormal relaxation increased myocardial stiffness, two hallmarks Non hemodynamic mechanisms such as metabolic electroly...

conclusions spironolactone combined with aceis or arbs leads to reduction of proteinuria in chronic kidney disease and therefore reduction of progression of the disease. objectives the study was designed to assess the effects of spironolactone as the aldosterone antagonist combined with acei or arb drugs to reduce proteinuria in chronic kidney disease to prevent its progression. patients and me...

Background: Patients who undergo major orthopedic surgery are at risk of acute kidney injury (AKI) due to blood loss, electrolyte disorders, infection, and the presence of other co-morbidities. In this study, the frequency and risk factors of AKI were investigated. Objective & Methods: This study is a cross-sectional-analytical study with a sample size of 180 people. The studied population wer...

Harmine is a harmal-derived alkaloid with antioxidant properties. The morphine produces free radicals and plays a key role in the pathogenesis of kidney disease. This study was designed to evaluate the effects of harmine against morphine- induced damage to the kidneys of rats. In this study, 64 male rats were randomly assigned to 8 groups: saline and morphine treated groups; harmine groups (5, ...

Abstract Background and Aims After nephrectomy kidney transplant donors lose 50% of their renal mass. Shortage long waiting list for deceased donor transplantation expanded the living criteria. The aim this study to identify pretransplant related factors associated with function decline. Method We retrospectively studied LDKT from one center in period 2013 -2022. Data was retrieved medical hist...