This study investigated the effectiveness of immobilizing Saccharomyces cerevisiae invertase (SInv) on magnetite nanoparticles to produce fructooligosaccharides (FOSs). Based existing literature and accompanied by parameter estimation, a modified kinetic model was employed represent kinetics sucrose hydrolysis transfructosylation using SInv immobilized nanoparticle surfaces. utilized simulate p...

UNLABELLED Studies have shown fibers to be effective in reducing the appearance of aberrant crypt foci (ACF) in rodents. OBJECTIVE The goal of this study was to investigate the preventive effects of fructooligosaccharide (FOS) and inulin prebiotics on the appearance of ACF in mice. MATERIALS AND METHODS The techniques used were: RT-PCR to evaluate the gene expression of p16, p21, p54, cycli...

Fructosyltransferase enzymes was isolated and partially purified from Aureobasidium pullulans. The enzyme being intracellular was recovered from the fungal sp. by extraction method using citrate buffer (0.1 M; pH 5.5). Enzyme was Semipurified by salt fractionation method which results increase in specific activity of the enzyme. Study regarding kinetic behavior indicates that the enzyme exhibit...

In this study the optimal amount of enriching Artemia franciscana with a synbiotic combination of Pediococcus acidilactici and fructooligosaccharide (FOS( was investigated. The experiment was conducted in a completely randomized design in ten treatments: multi-level probiotics P. acidilactici (1×109, 1×108 and 1× 107 CFU per L) and mul...

Lactobacillus acidophilus is a probiotic organism that displays the ability to use prebiotic compounds such as fructooligosaccharides (FOS), which stimulate the growth of beneficial commensals in the gastrointestinal tract. However, little is known about the mechanisms and genes involved in FOS utilization by Lactobacillus species. Analysis of the L. acidophilus NCFM genome revealed an msm locu...

This study investigates the treatment of non-alcoholic fatty liver disease (NAFLD) in rats with choline and fructooligosaccharide (FOS). The healthy control group received standard diet. The other three groups consisted of animals with NAFLD. Group Estr received standard diet; group Echo received standard diet plus choline (3 g/100 g diet); and group Efos received standard diet plus FOS (10 g/1...

Short-chain fructooligosaccharides (scFOS) and other prebiotics are used to selectively stimulate the growth and activity of lactobacilli and bifidobacteria in the colon. However, there is little information on the mechanisms whereby prebiotics exert their specific effects upon such microorganisms. To study the genomic basis of scFOS metabolism in Lactobacillus plantarum WCFS1, two-color microa...

Mycophenolate mofetil (MMF) is a selective inhibitor of Inosine-5′-monophosphate dehydrogenase. Gastrointestinal (GI) disturbances in immature ones are reported for MMF-induced compilations, which in the case of occurrence dose reduction is required. Thus, in the present study, the fructooligosaccharide raftilose® (RFT) was co-administrated with MMF to estimate the protective effect ...

The objective of this in vitro study was to evaluate the effects of combining a prebiotic with alfalfa on fermentation by laying hen cecal bacteria. Cecal contents from laying hens were diluted to a 1:3,000 concentration with an anaerobic dilution solution and added to serum tubes filled with ground alfalfa or a layer ration with or without fructooligosaccharide (FOS) prebiotic. Samples were pr...