Forty-four children, treated conservatively for fracture of the shaft of a femur, were studied radiographically to assess the consequent increase in longitudinal growth of the bone. Overgrowth averaged 8.1 mm and was shown to be significantly greater in boys than in girls. Overgrowth did not appear to be influenced by the age of the patient, the type of injury, the type or site of the fracture,...

events that leads to bony union of the broken fragments. After a fracture, the space between the ends of broken bones is filled with hematoma rich in pluripotential mesenchymal cells and cytokines. The tissue that forms within this space usually goes through a cascade of events that include cartilage formation, ossification, and remodeling phases. The roles of growth factors,1,2 ecosanoids,3 an...

There is an increasing need to assess the service life of components containing defect which operate at high temperature. This paper describes the current fracture mechanics concepts that are employed to predict cracking of engineering materials at high temperatures under static and cyclic loading. The relationship between these concepts and those of high temperature life assessment methods is ...

The aim of the present study was to observe the effect of varying the timing of surgery on the fracture healing process and the expression levels of vascular endothelial growth factor (VEGF) and bone morphogenetic protein (BMP)-2 in rats. A total of 192 rats underwent closed femur fracture modelling. The rats underwent open reduction and internal fixation surgery 1, 3, 5, 7, 11 and 14 days subs...

The rate-dependent fracture behavior of a 10-phr rubber-modified epoxy was investigated using double-cantilever-beam tests at various crosshead speeds. Dramatic rate effects were observed in the R-curve behavior and in the relationship between the applied energy-release rate and the crack velocity. Furthermore, a transition between fracture with toughening mechanisms operating (kinetic crack gr...

PURPOSE Previous studies have proved that vascular endothelial growth factor (VEGF) has a dual role in the promotion of new bone formation and blood vessel repair during fracture healing. However, how to introduce VEGF to a fracture site safely and effectively is still a challenge. This study aimed to prepare a VEGF-loaded nanographene coated internal fixation screw and to evaluate its effects ...

Floating ice shelves can exert a retentive and hence stabilizing force onto the inland ice sheet of Antarctica. However, this effect has been observed to diminish by the dynamic effects of fracture processes within the protective ice shelves, leading to accelerated ice flow and hence to a sealevel contribution. In order to account for the macroscopic effect of fracture processes on large-scale ...

This study discusses the results of a histological examination of bone calluses in the treatment of tibia fractures in sheep with the involvement of a semi-circular fixator. In all sheep, callus samples revealed the presence of well-developed, compact bone tissue in the area of fracture healing. It was found that the use of a semi-circular fixator promoted bone growth, and that it is an effecti...

Abstract The prevalence of mandibular fracture is relatively lower in the pediatric population compared to adults. The treatment of these fractures is more challenging for oral and maxillofacial surgeons due to the concerns regarding mandible growth and the presence of developing tooth buds. According to the literature, conventional methods (e.g., soft diets or closed red...

As long as bone repair and regeneration is considered as a complex clinical condition, the administration of more than one factor involved in fracture healing might be necessary. The effectiveness or not of bone morphogenetic proteins (BMPs) in association with other growth factors and with mesenchymal stem cells in bone regeneration for fracture healing and bone allograft integration is of gre...