A 42-year-old man presented with chronic, continuous, bifrontal pressure headaches, slightly worse in the morning, forgetfulness, and confusion. There was no history of prior CNS hemorrhage or infection. The neurologic examination was unremarkable. No papilledema was present. Neuroimaging demonstrated symmetric enlargement of the lateral ventricles, a slit-like third ventricle, and downwards tr...

AdaBoost can be derived by sequential minimization of the exponential loss function. It implements the learning process by exponentially reweighting examples according to classification results. However, weights are often too sharply tuned, so that AdaBoost suffers from the nonrobustness and overlearning. Wepropose a new boosting method that is a slight modification of AdaBoost. The loss functi...

A 73-year-old woman had progressive apathy, forgetfulness, and gait disturbance for 6 months. Neurologic examination showed inattentiveness, memory impairment, and broad-based gait. Noncontrast MRI was performed due to gadolinium allergy. MRI and contrast-enhanced CT scan revealed symmetric bilateral frontal cysts (figure 1A) and an anterior skull base nodule (figure 1, B and C). Surgery confir...

Most individual life insurance policies lapse, with lapsers cross-subsidizing non-lapsers. We show that and lapse patterns predicted by standard rational expectations models are the opposite of those observed empirically. propose two behavioral consistent evidence: (i) consumers forget to pay premiums (ii) understate future liquidity needs. conduct surveys a large insurer. New buyers believe th...

Abstract Background Patients’ failure to adhere TB treatment was a major challenge that leads poor outcomes. In Ethiopia, success low as compared with the global threshold. Despite various studies done in adherence, little known specifically continuation phase where is mainly patient-centered. This study aimed determine adherence and its determinants among adult patients during phase. Methods W...

Background: Hematological effects and digestive and neuro-psychological signs and symptoms are some manifestations of lead toxicity. However, there are conflicting reports of their prevalence among lead exposed workers and their relationship with blood lead levels (BLL). This case- control study assessed the relationship between BLL and hematological indexes and digestive (abdominal colic, ir...

A 71-year-old man presented with 6 years of forgetfulness, behavioral change, intrusive “growling” vocalizations, orthostatic headaches, and a cough.MRI brain was consistent with frontotemporal brain sagging syndrome (figure, A). He subsequently fell, hitting his chest on a chair, with immediate resolution of his cough, cognitive improvement, and corresponding radiologic desagging (figure, B; v...

Alzheimer’s Dementia (AD) is a disease of the elderly, although it tragically can affect individuals at younger ages. The age adjusted annual death rate, based on United States population data, shows a tenfold increase from 0.004/1000 in 1979 to 0.042/1000 in 1987. The cause for this dramatic change may be twofold. First, the true incidence or prevalence may have increased. Secondly, due to inc...

The elderly are particularly vulnerable to drug-induced morbidity. They may suffer from multiple medical problems leading to long-term drug use. Polypharmacy together with ageing-related changes in pharmacokinetics, pharmacodynamics and homeostatic mechanisms increases the risk of adverse drug reactions. Drug-related problems (adverse drug reactions, therapeutic failure and poisoning) are impor...

Case Report We report a case of gliomatosis cerebri with massive enlargement of the white matter commissural tracts (including the corpus callosum, the anterior commissure, and the fornices) that may have been directly responsible for obstruction of CSF pathways and subsequent hydrocephalus. A 64-year-old man had no significant medical history until 1 year before he died. At this time he showed...