introduction: epidermal growth factor receptor (egfr) has been shown to play a critical role in tumor cell growth and its overexpression has been observed in many epithelial tumors. in the field of cancer vaccine research, displaying the peptide mimotope on the surface of phage particles has shown promising results. methods: in this study using m13-pviii phage display system, two constructs wer...

Food allergy is a major public health problem in children, impacting upon the affected individual, their families and others charged with their care, for example educational establishments, and the food industry. In contrast to most other paediatric diseases, there is no established cure: current management is based upon dietary avoidance and the provision of rescue medication in the event of a...

Background Buckwheat (Fagopyrum esculentum) is not only common pseudo-cereal in Japan, Korea, and other East Asian countries, but also a health food and substitute for wheat flour in Western countries. Buckwheat allergy is an immunoglobulin E (IgE)-mediated hypersensitivity manifesting as severe and critical symptoms induced by ingestion or inhalation of even a small amount of the flour or food...

Peanut and tree-nut allergies have increased dramatically in prevalence, especially children. Historically, children with food been treated through strict avoidance of the allergen. Recently, an oral preparation peanut allergen (Palforzia) was approved for immunotherapy (ie, desensitization) 4 to 17 years old. This article reviews its role allergies.

While the efficacy of classical subcutaneous allergen-specific immunotherapy (ASIT) has been proven by a multitude of double-blind placebo-controlled trials for various allergens and clinical conditions such as allergic rhinoconjuncitivis, allergic bronchial asthma or insect venom anaphylaxis, patients suffering from food allergy are still left with the simple recommendation of avoidance. This ...

A1 Proceedings of 2016 China Cancer Immunotherapy Workshop, Beijing, China Bin Xue, Jiaqi Xu, Wenru Song, Zhimin Yang, Ke Liu and Zihai Li China Center for Food and Drug International Exchange (CCFDIE), Beijing, China; Center for Drug Evaluation (CDE) of the China Food and Drug Administration (CFDA), Beijing, China; Chinese American Hematologist and Oncologist Network (CAHON), New York, NY, USA...

72 The Choice of Hypoallergens for Fish and Peach to Develop Food Allergy Specific Immunotherapy (TheFAST Project) Laurian Zuidmeer-Jongejan, PhD, Serge Versteeg, Lars Poulsen, MD, PhD, Montserrat Fernandez-Rivas, MD, PhD, Marek L. Kowalski, MD, PhD, Nikos Papadopoulos, Adriano Mari, MD, Ines Swoboda, PhD, Michael Clausen, MD, PhD, Carsten Bindslev-Jensen, MD, PhD, Angela Neubauer, PhD, Stef Ko...

Food allergies, defined as an immune response to food proteins, affect as many as 8% of young children and 2% of adults in westernized countries, and their prevalence appears to be rising like all allergic diseases. In addition to well-recognized urticaria and anaphylaxis triggered by IgE antibody-mediated immune responses, there is an increasing recognition of cell-mediated disorders such as e...

72 The Choice of Hypoallergens for Fish and Peach to Develop Food Allergy Specific Immunotherapy (TheFAST Project) Laurian Zuidmeer-Jongejan, PhD, Serge Versteeg, Lars Poulsen, MD, PhD, Montserrat Fernandez-Rivas, MD, PhD, Marek L. Kowalski, MD, PhD, Nikos Papadopoulos, Adriano Mari, MD, Ines Swoboda, PhD, Michael Clausen, MD, PhD, Carsten Bindslev-Jensen, MD, PhD, Angela Neubauer, PhD, Stef Ko...

72 The Choice of Hypoallergens for Fish and Peach to Develop Food Allergy Specific Immunotherapy (TheFAST Project) Laurian Zuidmeer-Jongejan, PhD, Serge Versteeg, Lars Poulsen, MD, PhD, Montserrat Fernandez-Rivas, MD, PhD, Marek L. Kowalski, MD, PhD, Nikos Papadopoulos, Adriano Mari, MD, Ines Swoboda, PhD, Michael Clausen, MD, PhD, Carsten Bindslev-Jensen, MD, PhD, Angela Neubauer, PhD, Stef Ko...