نتایج جستجو برای: fomepizole

تعداد نتایج: 163  

Journal: :The Biochemical journal 1998
D E Jensen G K Belka G C Du Bois

An enzyme isolated from rat liver cytosol (native molecular mass 78. 3 kDa; polypeptide molecular mass 42.5 kDa) is capable of catalysing the NADH/NADPH-dependent degradation of S-nitrosoglutathione (GSNO). The activity utilizes 1 mol of coenzyme per mol of GSNO processed. The isolated enzyme has, as well, several characteristics that are unique to alcohol dehydrogenase (ADH) class III isoenzym...

2016
Janaina A. Simplicio Ulisses Vilela Hipólito Gabriel Tavares do Vale Glaucia Elena Callera Camila André Pereira Rhian M Touyz Rita de Cássia Tostes Carlos R. Tirapelli

Background: The mechanism underlying the vascular dysfunction induced by ethanol is not totally understood. Identification of biochemical/molecular mechanisms that could explain such effects is warranted. Objective: To investigate whether acute ethanol intake activates the vascular RhoA/Rho kinase pathway in resistance arteries and the role of NAD(P)H oxidase-derived reactive oxygen species (...

Journal: :American journal of physiology. Endocrinology and metabolism 2008
Patricia E Molina

WITH OVER 60% OF THE POPULATION consuming alcohol during the past year, and 32% admitting to engaging in alcohol binging episodes, alcohol abuse continues to be a comorbid condition for several diseases, but in particular for liver disease. Liver disease is one of the most salient pathophysiological conditions resulting from alcohol abuse and a major cause of alcoholrelated morbidity and mortal...

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