Tumor necrosis factor-alpha (TNF) is a cytokine produced not only by various cells of the immune system, but also by various cells in the reproductive system. We have demonstrated that oocytes are an important source of TNF and that the onset of oocytic TNF expression occurs around birth. TNF receptors are localized on oocytes, granulosa cells and interstitial cells allowing for the possibility...

The effect of a purified bovine thymus gland extract (Dr. Kurt Mulli, GmbH, Hamburg, West Germany) was studied in 12-week old male Wistar rats on the following: thyroid weights and morphology, T3-T4 serum levels, thyroid lactic dehydrogenase, ATP-ase, acid phosphatase, and non-specific esterase activities. Thymus extract was administered intramuscularly daily for 21 days at doses of 0.5, 1.0 an...

Introduction: Dentigerous cyst is an odontogenic cyst. It caused by accumulation of fluid between the epithelium crown and unerupted tooth. attached to neck tooth its size increases expansion follicle. This most commonly affects impacted 3rd molar maxillary canine.
 Case Report: In present paper, we report a case dentigerous associated with canine in 13year aged female.
 Conclusion: T...

Lanthanum tracer and freeze-fracture electron microscope techniques were used to study junctional complexes between granulosa cells during the differentiation of the rabbit ovarian follicle. For convenience we refer to cells encompassing the oocyte, before antrum and gap junction formation, as follicle cells. After the appearance of an antrum and gap junctions we call the cells granulosa cells....

Rising serum FSH levels is one of the earliest signs of human female reproductive aging. Whether or not elevated FSH remains a passive reflection of a diminishing ovarian follicle pool or actively contributes to declining female fertility with age has not been established. We therefore investigated female reproduction in mice expressing progressively rising serum levels of transgenic human FSH ...

The ultrastructure of follicle cells has been compared to that of developing oocytes in the marine crustacean isopod, Idotea balthica basteri, at different periods of the molting cycle. There was a distinct change in the shape and size of the follicles and in their relation to each other and to the oocytes. During stage 1 of vitellogenesis (molting cycle period C), spaces between the follicles ...

Physiologically, the size of the primordial follicle pool determines the reproductive lifespan of female mammals, while its establishment largely depends on a process of germline cyst breakdown during the perinatal period. The mechanisms regulating this process are poorly understood. Here we demonstrate that c-Jun amino-terminal kinase (JNK) signaling is crucial for germline cyst breakdown and ...