GATA factors establish transcriptional networks that control fundamental developmental processes. Whereas the regulator of hematopoiesis GATA-1 is subject to multiple posttranslational modifications, how these modifications influence GATA-1 function at endogenous loci is unknown. We demonstrate that sumoylation of GATA-1 K137 promotes transcriptional activation only at target genes requiring th...

Both the similar and different effects of freezing drizzle, sleet and snow on microphysical properties of supercooled fog were analyzed for fourteen events during a comprehensive wire icing, fog, and precipitation observation experiment conducted at Enshi radar station (30◦17′N, 109◦16′E; 1722 m a.s.l.) on a hilltop in Shibanling, Hubei, China. Liquid precipitation is in a relatively stable for...

Chromatin-modifying complexes such as the NuRD complex are recruited to particular genomic sites by gene-specific nuclear factors. Overall, however, little is known about the molecular basis for these interactions. Here, we present the 1.9 Å resolution crystal structure of the NuRD subunit RbAp48 bound to the 15 N-terminal amino acids of the GATA-1 cofactor FOG-1. The FOG-1 peptide contacts a n...

In C. elegans, the zinc-finger protein TRA-1A is thought to be the final arbiter of somatic sexual identity. We show that fog-3, which is required for germ cells to become sperm rather than oocytes, is a target of TRA-1A. First, northern analyses and RT-PCR experiments indicate that expression of fog-3 is controlled by tra-1. Second, studies of double mutants show that this control could be dir...

The specification of a germ cell as sperm or oocyte and determination of cell number remain unsolved questions in developmental biology. This paper examines Caenorhabditis elegans FOG-1, a CPEB-related RNA-binding protein that controls the sperm fate. We find that abundant FOG-1 protein is observed transiently in germ cells just prior to their expression of an early sperm-differentiation marker...

Intermediate polars range from systems which accrete entirely via discs (e.g. EX Hya) through systems which combine disc and disc-overrow accretion (e.g. FO Aqr) to discless accretors (e.g. RX 1712{ 24). The accretion curtain model provides a good description of the optical spin-pulses, while in the X-ray regime, occultation combines with absorption to create complex pulse-prooles.

Organic wastes, such as fats, oils, and grease (FOG), are good substrates for biogas production because of their high methane yield potential. FOG are hydrolyzed to glycerol and long-chain fatty acids(LCFA), and the degradation of LCFA takes place through the β-oxidation pathway which has been reported as the rate-limiting step of the whole anaerobic digestion process. This paper reviews the sc...

The current study investigated age-related differences in the detection of collision events in fog. Observers were presented with displays simulating an object moving towards a driver at a constant speed and linear trajectory. The observers’ task was to detect whether the object would collide with them. Fog and display duration of the object were manipulated. We found that performance decreased...

Field tests concerning a fog mesh method for fog removal are discussed. The first tests were performed at the Pyhäsalmi Mine, Finland. As this study gave promising results, further studies were completed at the Orivesi Mine. The results of these most recent field tests are presented and the two studies are compared. The Orivesi test set consisted of four materials. These included air filter fab...

The aim of this study was to elucidate the adverse respiratory effects of naturally occurring acid fog. In total, 102 adult asthmatic patients (44 nonatopic and 58 atopic) were studied for a 2 yr period (January 1992 to December 1993) in Kushiro, a city with only a small industrial area, located in the northern-most island in Japan. Fog occurred on 378 out of 731 days, and the acidity of the fo...