Initial models of AMPA receptor assembly postulated the unrestricted stochastic association of individual subunits. The low Ca(2+) permeability and nonrectified current-voltage relationship of most native AMPA receptors were ascribed to dominant effects of the glutamate receptor 2 (GluR2) subunit. A recent model, however, proposes instead the preferred assembly of GluR1 and GluR2 subunits into ...

all practical digital circuits are usually a mixture of combinational and sequential logic. flip–flops are essential to sequential logic therefore fuzzy flip–flops are considered to be among the most essential topics of fuzzy digital circuit. the concept of fuzzy digital circuit is among the most interesting applications of fuzzy sets and logic due to the fact that if there has to be an ultimat...

The relative stability of cholesterol in cellular membranes and the thermodynamics of fluctuations from equilibrium have important consequences for sterol trafficking and lateral domain formation. We used molecular dynamics computer simulations to investigate the partitioning of cholesterol in a systematic set of lipid bilayers. In addition to atomistic simulations, we undertook a large set of ...

The rates of spontaneous interbilayer and transbilayer exchange of [3H]dimyristoylphosphatidylcholine ([3H]DMPC) were examined in DMPC and DMPC/dimyristoylphosphatidylethanolamine (DMPE) large unilamellar vesicles in the liquid-crystalline-, gel-, and mixed-phase states. DMPC desorption rates from either gel or liquid-crystalline phases containing DMPE are very similar to the corresponding rate...

The sequential element (flip-flop) is a basic building block to design any clocking system, which consists of the clock distribution tree and flip-flops. A large portion of the on chip power is consumed by the clocking system the total power consumption of the clocking system depends on both clocking distribution tree and also the register elements (flip-flops). The power consumption of registe...

The distribution of terminal-sequence orientations in the viral DNA of bovine parvovirus (BPV), an autonomous parvovirus, was studied by end labeling and restriction enzyme digestion and also by cloning. The left (3') end of the minus strand of BPV was found in two alternative sequence orientations (designated as flip and flop, which are reverse complements of each other), with a 10-fold excess...

All practical digital circuits are usually a mixture of combinational and sequential logic. Flip–flops are essential to sequential logic therefore fuzzy flip–flops are considered to be among the most essential topics of fuzzy digital circuit. The concept of fuzzy digital circuit is among the most interesting applications of fuzzy sets and logic due to the fact that if there has to be an ultimat...