نتایج جستجو برای: flavones

تعداد نتایج: 1217  

1991
A. K. Srivastava R. L. Khare R. K. Udadhyay A. K. Jha J. S. Dangi Naresh Talwar

A flavones glycoside isolated from the bark of ayurvedic plant, Nyctanthes arbortristis was subjected to various pharmacological studies. The glycoside was found to be effective on, cardiovascular system and smooth muscles of intestine but no significant effect was found on CNS. The glycoside exhibited promising anti-inflammatory activity.

Journal: :Chemical & pharmaceutical bulletin 2010
Masato Matsugi Masaki Takeda Ayano Takahashi Takahide Tazaki Hiroto Tamura Takayuki Shioiri

A variety of 5,4'-disubstituted flavones, which are anticipated to be androgen receptor antagonists to treat diseases mediated by the androgen receptor, were synthesized. It was found that an intramolecular ipso-substitution reaction via cesium enolate using 2-fluoro-6-hydroxyacetophenone and various benzoyl chlorides was effective in the preparation of 5-hydroxy-4'-alkylflavones.

Journal: :The Journal of organic chemistry 2005
Julio A Seijas M Pilar Vázquez-Tato Raquel Carballido-Reboredo

[reaction: see text] Eco-friendly direct solvent-free synthesis of flavones is achieved by microwave irradiation of phloroglucinol and beta-ketoesters. Heating with microwaves versus under classical conditions was shown to be higher yielding, cleaner, and faster. The reaction goes through a cycloaddition of an alpha-oxo ketene intermediate followed by an uncatalyzed thermal Fries rearrangement.

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2014
Mahmoud Nawwar Amani El-Mousallami Sahar Hussein Amani Hashem Mona Mousa Ulrike Lindequist Michael Linscheid

Three hitherto unknown di-O-xylosyl-C-glycosyl flavones were isolated from the leaves of Caesalpinia ferrea. The structures of all isolated compounds were elucidated by conventional methods and spectroscopic analysis, including 1D and 2D NMR, as well as by HRESIMS.

Journal: :African Journal of Traditional, Complementary and Alternative Medicines 2018

N. Kharazian

Eight Salvia L. species including S. spinosa L., S. reuterana Boiss., S. macrosiphon Boiss., S. syriaca L., S. nemorosa L., S. virgata Jacq., S. sharifii Rech. f. & Esfand. and S. mirzayanii Rech. f. & Esfand. were studied for flavonoid compounds. These constituents were analyzed using two-dimensional maps on silica gel 60F thin layer chromatography. The flavonoid compounds of each species were...

Journal: :Chemical & pharmaceutical bulletin 2003
Muntha Kesava Reddy Mopuru Vijaya Bhaskar Reddy Galla Jayakrishna Duvvuru Gunasekar Cristelle Caux Bernard Bodo

Two new flavonoids, 5, 7, 2', 5'-tetramethoxyflavanone (1) and 5-hydroxy-7, 2'-dimethoxyflavone (2), together with two known flavones, skullcapflavone I (3) and echioidin (4) were isolated from the whole plant of Andrographis rothii. The structures of the new compounds were established by extensive one- and two-dimensional (1D- and 2D-) NMR spectral studies.

Journal: :Organic & biomolecular chemistry 2011
Guoping Peng Yidan Du Yingling Wei Jingming Tang Ai-Yun Peng Liqun Rao

Five flavones possessing one to four phenolic groups were fully phosphorylated efficiently and the obtained compounds showed excellent pancreatic cholesterol esterase (CEase) inhibitory activities with IC(50) in the nanomolar range, which were much more potent than their parent compounds. The inhibition mechanism and kinetic characterization studies indicate that they are irreversible competiti...

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