Chronic wasting disease (CWD) status and PrP genotypes were determined for a group of 133 wild white-tailed deer in a 780 acre enclosure in western Nebraska, USA. Approximately half of the deer tested showed evidence of PrPd in the brainstem or lymphoid tissues. Four PRNP alleles encoding amino acid substitutions were identified, with substitutions at residues 95 (Q-->H), 96 (G-->S) or 116 (A--...

in order to investigate production potential, variation and genetic similarity of selected iranian smooth brome grass (bromus intermis) genotypes, an experiment was conducted using clonally propagated materials. genotypes were evaluated for agronomic, phenological and morphological characteristics under a randomized complete block design during 2005 and 2006. results showed that there were sign...

abstract: methylenetetrahydrofolate reductase (mthfr) is a key enzyme regulating folate metabolism, which affects dna methylation and synthesis. one of the most important polymorphisms identified in the mthfr gene is c677t. mthfr activity is lowered in individuals with 677tt genotype. using pyrosequencing, we analyzed the mthfr genotypes in 118 colorectal cancer patients and 189 normal matched ...

BACKGROUND/AIMS Age related macular degeneration (AMD) is a complex disorder leading to loss of central vision, and identification of risk factors associated with susceptibility to AMD has been a key objective for ophthalmic genetics research for almost a decade. This association study has examined genetic polymorphisms in 12 candidate genes as possible risk factors for predisposition to the de...

background: approximately 600,000 deaths occur every year as a result of the acute and chronic consequences of hepatitis b virus infection. ten different hepatitis b virus genotypes have been identified with distinct geographical distributions. different clinical outcomes, including the rate of mutations, development of hepatocellular carcinoma, chronicity, response to treatment, transplantatio...

BACKGROUND: Group A bovine rotavirus (BRV-A) is one of the most important causes of gastroenteritis and diarrhea in newborn calves. OBJECTIVES: Major types of BRV-A in Tehran, Alborz and Qazvin were detected in this study. METHODS: A total 125 fecal samples of calves showing clinical signs of diarrhea were collected from 26 industrial dairy farms located in the provinces of Tehran, Alborz and Q...

The main objective of the study was to find genetic variants that in combination are significantly associated with bipolar disorder. In previous studies of bipolar disorder, combinations of three and four single nucleotide polymorphisms (SNP) genotypes taken from 803 SNPs were analyzed, and five clusters of combinations were found to be significantly associated with bipolar disorder. In the pre...