BACKGROUND Patients with unprovoked venous thromboembolism (VTE) are at an increased risk of mortality, but whether their cardiovascular risks also increase remains to be determined. We aimed to investigate the factors associated with overall mortality and major adverse cardiovascular events in patients with unprovoked VTE. METHODS AND RESULTS We identified 2154 patients newly diagnosed with ...

129 A n accurate diagnosis built on history, physical examination, and testing is the critical first step in successful management of epilepsy and isolated seizures in children. Determining the risk for recurrence is, of course, the paramount concern to both clinician and parents. In the United States, the estimates of recurrence risk range from 23% to 71%, with most of the variation in estimat...

 ABSTRACT Background: The efficacy of anticonvulsants after a first seizure is uncertain the more predictable the time and the type of recunent seizure, the more preventable the probable events. This study was conducted to evaluate sirnilmity of type and time of a first seizure and its recutTence in children. Methods: 174 children with at least two separate seizures were taken into account. Res...

PURPOSE The aim of the present study was to investigate the epidemiologic profile of epileptic seizures in the general population of a defined area of Northwest Greece. We also investigated the frequency of epilepsy in the same population. METHODS The study area was the District of Corfu representing a population of about 11,3000 inhabitants. Cases have been recorded prospectively in the fram...

BACKGROUND The optimal duration of anticoagulation for a first episode of unprovoked venous thromboembolism (VTE) is uncertain. Methods for predicting risk for recurrence may identify low-risk patients who are less likely to benefit from prolonged anticoagulation. PURPOSE To synthesize evidence evaluating the value of D-dimer as a predictor of recurrent disease in patients who have stopped an...