part of the blame for this age-related decline belongs to lazy stem cells that sit idly by rather than repair injuries. Normally, injuries to muscle tissue activate the stem cell-like satellite cells, which then multiply and differentiate into myoblasts that can fuse with and thus repair injured muscle fibers. The injury-induced proliferation is a function of the Notch pathway. But Rando's grou...

INTRODUCTION THE incidence of primary and secondary syphilis has shown a steady increase in Great Britain in the last decade, from a figure of 1,162 in 1970 to 1,543 in 1979 for England and Wales. The incidence in Northern Ireland has been somewhat more sporadic (Figure) but we have found, in common with our colleagues in the United Kingdom,' a tendency to forget these conditions in arriving at...