BACKGROUND The study aimed to describe the characteristics of women treated for recently-diagnosed osteoporosis, to identify variables associated with different treatment regimens and to assess impact on quality of life. METHODS This is an observational, cross-sectional pharmacoepidemiological study performed in France. A random sample of 684 general practitioners, gynaecologists and rheumato...

Four quantitative reverse transcription-PCR (RT-PCR) methods were compared to evaluate the time course of mRNA formation and decay. Mouse fibroblasts (NIH 3T3) transfected with the human beta-globin open reading frame/c-myc 3'-untranslated region chimeric gene under control of the c-fos promoter (fos-glo-myc) were used for serum-inducible transcription. The amount of fos-glo-myc mRNA, relative ...

BACKGROUND The study was planned to assess effect of physical exercise on bone remodeling in type I diabetics with osteopenia. METHODS Twenty-four type I diabetes mellitus (DM1) with osteopenia (10 females and 14 males) were compared to thirty-eight age- and sex-matched healthy control individuals (20 females and 18 males) for biochemical and radiologic parameters of bone mass. Laboratory inv...

UNLABELLED In March 2008, FRAX, developed by Kanis and collaborators in the University of Sheffield and supported by the World Health Organization, became available online to calculate absolute risk of osteoporotic fracture in the next 10 years. OBJECTIVE To analyze the risk of fracture calculated by FRAX and its determinants in the patients sent to a densitometry unit for bone mineral densit...

We examined the suitability of a rapid immunological technique to determine the amount of aspartate aminotransferase (EC 2.6.1.1) isoenzymes in human serum or tissue extracts. Purified isoenzymes were adsorbed as a monolayer to the surface of an indium metal film on glass. The enzyme retains immunological reactivity, allowing the specific binding of aspartate aminotransferase antibodies at the ...

An increasing number of men with prostate cancer being treated with androgen-deprivation therapy (ADT) are at increased risk for developing osteoporosis. Osteoporosis often is overlooked in men and can have significant adverse economic effects and reduce quality of life, particularly if a fracture occurs. Nurses play a major role in identifying men who are at risk because of lifestyle factors a...

Measurement of combustion gas by high-energy X-ray Compton scattering is reported. The intensity of Compton-scattered X-rays has shown a position dependence across the flame of the combustion gas, allowing us to estimate the temperature distribution of the combustion flame. The energy spectra of Compton-scattered X-rays have revealed a significant difference across the combustion reaction zone,...

Introduction: Bone mineral density (BMD) has been identified as a major factor in spine construct strength, with failures resulting in pedicle screw loosening and pullout [2,3]. Computed tomography (CT) scans have been shown to effectively measure BMD [1,4]. Previous research has utilized this linear correlation of CT Hounsfield Units (HU) to BMD in order to determine BMD as a function of anato...

osteoporosis (op) is a frequent complication of rheumatoid arthritis (ra) and longitudinal studies have documented increased rate of bone loss in ra patients. to determine the frequency of low bone mass as well as the influence of disease duration and corticosteroid use on bone mass in patients with ra, 88 patients with ra and 112 age matched controls were studied. bone densitometry was perform...