perfluorooctanesulfonate (pfos) is a widely spread environmental contaminant. it accumulates in the brain and has potential neurotoxin effects. due to chemical properties, pfos shows persistency in the environment and therefore has potential hazardous effect. the risk of possible intra uterine exposure to pfos poses a health concern for developmental effects. the goal of this study was survey o...

background: silymarin is a flavonolignan that has been the subject of research to evaluate the beneficial properties for decades. silymarin has been known for its potent cytoprotective, hepatoprotective and antioxidant activities. the goal of the present study was to gain a deeper understanding of possible molecular mechanisms of apoptosis of the injuries induced by silymarin on balb/c mice fet...

background: several studies have assessed the correlation of fetal choroid plexus cyst (cpc) and the risk of congenital anomalies, but few ones have discussed isolated cpc (with no other abnormal sonographic finding). objective: the aim of this study was to determine the outcome of isolated fetal choroid plexus cyst and to specify its clinical significance. materials and methods: this cross sec...

The influence of priority factors such as vitamins during the period fetal development in three trimesters is considered. analysis dynamics fetus, taking into account saturation nutrients and food products. main influencing fetus have been investigated, types products that provide a rational diet for pregnant women identified. Developed mathematical model differentiated dietary nutrition prenat...

background: sulfatase 1 ( sulf1 ) function is to remove the 6-o-sulphate group from heparan sulfate. this action changes the binding sites of extracellular growth factors. sulf1 expression has been reported to be changed in angiogenesis. we hypothesized that single nucleotide polymorphisms (snps) of sulf1 would impact clinicopathologic characteristics. objective: study of sulf1 gene polymorphis...

Miconazole is an imidazole antifungal agent, commonly applied topically to the skin or mucous membranes. The aim of this study was to examine the alternative method for gaining mechanism or the bimolecular changes caused by the possible teratogenic effects of Miconazole on mice fetus brain tissue using FTIR-Microspectroscopy. The mice were injected with Miconazole (60 mg/Kg) on gestation day 9....