Streptococcus pneumoniae, a neuraminidase-producing pathogen, can cause invasive pneumococcal disease (IPD) with or without hemolytic uremic syndrome (HUS) in humans. We aimed to identify serum sialoglycoproteins that are targeted by neuraminidases in severe pneumococcal infection. We hypothesized that serum sialoglycoprotein such as fetuin-A can serve as a biomarker to predict IPD or HUS. We c...

Mineral formation is regulated by molecular based promoters or inhibitors in biological systems. Among serum proteins, fetuin-A can effectively inhibit unwanted calcification vivo via forming fetuin-mineral complexes called calciprotein particles (CPPs). Here, the and phase transformation mechanisms of CPPs are investigated detail combining situ potentiometric measurements solid characterizatio...

This comment describes the study by Jersmann and co-workers in this issue of Clinical Science reporting the results of a study of the role of the serum glycoprotein fetuin in the uptake of apoptotic cells by macrophages. They show that fetuin is able to stimulate the macropinocytosis of apoptotic cells in vivo, which would be therapeutically useful following chemotherapy when the increased numb...

Introduction: Cardiovascular disease, diabetes, and fatty liver are now considered the major causes of mortality in developing countries. The present study investigates the effect of twelve weeks of combined training with and without canagliflozin consumption on fetuin-A and fetuin B in type 2 diabetic men. Materials and Methods: Forty- four men (25-40 years ) who had type two diabitiac were r...

THE EFFECT OF 8 WEEKS COMBINED TRAINING ALONG WITH USE MULBERRY LEAF EXTRACT ON SERUM LEVELS FETUIN A AND B IN ELDERLY MEN TYPE DIABETES 2

The present work aimed to magnetize Parkia pendula seeds gum and use it as a matrix for Concanavalin A covalent immobilization. This composite was applied in affinity purification of glycoconjugates. Parkia pendula seeds were hydrated and the gum provenient from the supernatant was precipitated and washed with ethanol and dried. The gum was magnetized in co-precipitation using solutions of Fe+2...

Giriş ve Amaç: Bu çalışmada ateroskleroz etyolojisinde rol oynadığı ileri sürülen 25OH-vitamin D, Matrix Gla Protein (MGP), Fetuin-A, Asimetrik Dimetil Arjinin (ADMA) belirteçleri ile koroner arter hastalığı arasındaki ilişki araştırıldı.
 Gereç Yöntemler: amaçla çalışmaya ön tanısı anjiyografi işlemi uygulanmış olan normal saptanan 40 olgu ile, en az bir arterinde %70 üzerinde darlık olma...

BACKGROUND AND OBJECTIVES Cardiovascular disease in chronic kidney disease (CKD) is explained in part by traditional cardiovascular risk factors; by uremia-specific factors; and by abnormalities of mineral metabolism, factors involved in its regulation, and in the vascular calcification process. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS In an unselected population of 177 patients with cal...