Cytochrome c (Cyt c) is a heme protein involved in electron transfer and also in apoptosis. Its heme iron is bisaxially ligated to histidine and methionine side chains and both ferric and ferrous redox states are physiologically relevant, as well as a ligand exchange between internal residue and external diatomic molecule. The photodissociation of internal axial ligand was observed for several ...

In a double-blind trial the response to treatment with Ferro-Gradume (a slow-release preparation of ferrous sulphate) has been compared in the same individuals with the response to ferrous fumarate in a single daily dose regimen using a similar dose of iron. No significant difference was found in the therapeutic response or in the incidence of side-effects between the two preparations.

Iron is the fourth most abundant element on Earth and is essential for almost all living organisms. However, it is not accessible to cells in every environment. Ferric iron solubility is low at physiological pH, and in aerobic environments, ferrous iron is highly toxic. Thus, iron is not free but bound to proteins [Clarke et al., 2001; Taylor and Kelly, 2010]. In complex organisms, the majority...

Acidithiobacillus ferrooxidans is a strict acidophilic chemolithoautotrophic bacterium that obtains its energy from reduced inorganic sulfur species or ferrous iron oxidation under aerobic conditions. Carbon felt electrodes were pre-colonized by A. ferrooxidansATCC 23270T using ferrous iron or sulfur as electron donors, via the addition (or not) of a mixture of C14 acyl-homoserine lactones (C14...

To study the impact of changes in groundwater flow and chemistry on acidity export from sediments in acid mine drainage (AMD) polluted lakes, a column experiment was carried out. Schwertmannite rich sediment was subjected to three different flow rates (0, 5, and 20 L m(-2) a(-1)), two percolate chemistries (1/1 mmol L(-1) vs 10/15 mmol L(-1) sulfate/ferrous iron, pH 5), and DOC input (approxima...

BACKGROUND Phytic acid is a strong inhibitor of iron absorption from fortified foods. In adults, this inhibitory effect can be overcome by adding ascorbic acid with the iron fortificant or by using a "protected" iron compound such as NaFeEDTA. In addition, the use of NaFeEDTA as an iron fortificant has been reported to increase zinc absorption in adult women. No information is available on iron...

Lauha Bhasma, an ayurvedic drug, is widely used in iron deficiency anaemia, this ancient drug is claimed to be better absorbed gastrointestinally, and is also claimed to be devoid of the usual side effects associated with administration of the allopathic iron preparations, Physical and chemical methods of standardization required for any quality preparation, is not found in the ayurvedic and th...

The utility of employing biogenerated ferric iron as an oxidant for the recycling of scrap metal has been demonstrated using continuously growing cells of the extremophilic organism Acidithiobacillus ferrooxidans. A ferric iron rich (70 mol%) lixiviant resulting from bioreactor based growth of A. ferrooxidans readily solubilized target scrap metal with the resultant generation of a leachate con...

We demonstrate that the unique green algal iron assimilatory protein, FEA1, is able to complement the Arabidopsis iron-transporter mutant, irt1, as well as enhance iron accumulation in FEA1 expressing wild-type plants. Expression of the FEA1 protein reduced iron-deficient growth phenotypes when plants were grown under iron limiting conditions and enhanced iron accumulation up to fivefold relati...