Endocrine disorders are the most common endocrinopathies. Thyroid hormone levels can affect the serum Ferritin level (Iron storage Protein) especially in females. 25 patients of clinically established patients of thyroid abnormality attending Out Patient Departments, MDM hospital Jodhpur (Rajasthan) were compared with 25 healthy subjects of either sex in Department of Biochemistry, Dr S. N. Med...

Several markers have been studied for their ability to make the CNS infiltration diagnosis earlier and more precise; previous studies showed that CSF ferritin concentrations were higher in patients with malignant invasion of CNS. The objective was to determine the importance of CSF ferritin as a biomarker for the diagnosis of CNS neoplastic infiltration. This study is based on 93 CSF samples, d...

To test the hypothesis that the quantities of circulating transferrin receptors are reduced in iron overload, we studied serum transferrin receptors and indirect measures of iron status in 150 subjects from rural Zimbabwe. We found significant inverse correlations between serum concentrations of transferrin receptors and ferritin, the ratio of ferritin to aspartate aminotransferase, and transfe...

Nitric oxide (NO) is a signaling molecule that plays a critical role in the activation of innate immune and inflammatory responses in animals. During the last few years, NO has also been detected in several plant species and the increasing number of reports on its function in plants have implicated NO as an important effector of growth, development and defense. Analogously to animals, NO has be...

Ferritin is a protein found in reticuloendothelial system and does not work only as a mid-size protein during Hemoglobin synthesis but also as storage protein for iron delivery. This cross sectional study was conducted in District Shaheed Benazirabad during the period of August 2015 to March 2016, for obtaining credible and consolidated data. In present study we investigated BMI, Hb and S.f lev...

In the current study it was found that K-562 erythroleukemia cells express the superheavy (S) inKNA and the 43Kd S peptide which were recently discovered in activated T-lymphocytes. The S mRNA was iden tified by its cross-hybridization with ferritin H complementary DNA probe and the S peptide (M, 43,000) was identified by its immunoprecipitation with CM-H-9 monoclonal antibody specific for plac...

The mechanisms that regulate the expression of the H chain of the iron storage protein ferritin in Friend erythroleukemia cells (FLCs) after exposure to hemin (ferric protoporphyrin IX), protoporphyrin IX, and ferric ammonium citrate (FAC) have been investigated. Administration of hemin increases the steady-state level of ferritin mRNA about 10-fold and that of ferritin protein expression 20-fo...

In animal cells specialized for iron storage, iron-induced accumulation of ferritin is known to result from a shift of stored mRNA from the ribonucleoprotein fraction to polysomes. Previous reports with bean leaves suggested that in plants iron induction of ferritin synthesis would result from a regulation at the transcriptional level (F van der Mark, F Bienfait, H van der Ende [1983] Biochem B...

BACKGROUND Elevated serum ferritin concentration is associated with insulin resistance and diabetes. Recently it has also been described in gestational diabetes mellitus (GDM). OBJECTIVE A prospective study was done to determine whether there was a relationship between serum ferritin concentration in early pregnancy and the risk of GDM. MATERIALS AND METHODS A study was performed on 1,384 p...