OBJECTIVE To evaluate the associations of dietary fiber after myocardial infarction (MI) and changes in dietary fiber intake from before to after MI with all cause and cardiovascular mortality. DESIGN Prospective cohort study. SETTING Two large prospective cohort studies of US women and men with repeated dietary measurements: the Nurses' Health Study and the Health Professionals Follow-Up S...

BACKGROUND Computer-aided diagnosis for screening utilizes computer-based analytical methodologies to process patient information. Glaucoma is the leading irreversible cause of blindness. Due to the lack of an effective and standard screening practice, more than 50% of the cases are undiagnosed, which prevents the early treatment of the disease. OBJECTIVE To design an automatic glaucoma diagn...

OBJECTIVE The aetiology of primary biliary cirrhosis (PBC) is largely unknown. Previous studies have indicated that both environmental and genetic risk factors may be important. DESIGN We undertook a large case-control study to study possible risk factors in more detail. All patients were sent postal questionnaires on risk factors. PATIENTS We identified two sets of PBC cases from a geograp...

AIMS To assess the effects of low-dose (LD) and high-dose (HD) ablation on acute and chronic success in patients with atrial fibrillation (AF). While the concept of visually guided pulmonary vein isolation (PVI) has been established little is known on energy titration using laser ablation. METHODS AND RESULTS In 60 patients with AF, PVI using the endoscopic ablation system (EAS) was performed...

BACKGROUND A phase 3 trial was conducted to evaluate the efficacy of a prophylactic quadrivalent vaccine in preventing anogenital diseases associated with human papillomavirus (HPV) types 6, 11, 16, and 18. METHODS In this randomized, placebo-controlled, double-blind trial involving 5455 women between the ages of 16 and 24 years, we assigned 2723 women to receive vaccine and 2732 to receive p...

* This is Paper No. 18 of a series on "The Formation of Fibrin and the Coagulation of Blood" from the University of Wisconsin, supported in part by research grants from the National Institutes of Health, Public Health Service. 1 Laki, K., Arch. Biochem. Biophys., 32, 317 (1951). 2 L6rand, L., Nature, 167, 992 (1951). Steiner, R. F., and Laki, K., Arch. Biochem. Biophys., 34, 24 (1951). 4Shulman...

Vol. 26, No. 6, 2014 785 Received September 5, 2013, Revised January 18, 2014, Accepted for publication February 1, 2014 Corresponding author: Tae Yoon Kim, Department of Dermatology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Korea. Tel: 82-2-2258-1380, Fax: 82-2-599-9950, E-mail: [email protected] This is ...

BACKGROUND Little information is available regarding variations in diabetes mellitus (DM) outcomes by race at the level of individual physicians. METHODS We identified 90 primary physicians caring for at least 5 white and 5 black adults with DM across 13 ambulatory sites and calculated rates of ideal control of hemoglobin A(1c) (HbA(1c)) (<7.0%), low-density lipoprotein cholesterol (LDL-C) (<...

BACKGROUND During most COPD exacerbations, patients continue to live in the community but there is little information on changes in activity during exacerbations due to the difficulties of obtaining recent, prospective baseline data. METHODS Patients recorded on daily diary cards any worsening in respiratory symptoms, peak expiratory flow (PEF) and the number of steps taken per day measured w...

BACKGROUND The healthiest dietary pattern for myocardial infarction (MI) survivors is not known. Specific long-term benefits of a low-carbohydrate diet (LCD) are unknown, whether from animal or vegetable sources. There is a need to examine the associations between post-MI adherence to an LCD and all-cause and cardiovascular mortality. METHODS AND RESULTS We included 2258 women from the Nurses...