MRI, enabling in vivo analysis of cortical morphology, offers a powerful tool in the assessment of brain development and pathology. One of the most ubiquitous measures used-the thickness of the cortex-shows abnormalities in a number of diseases and conditions, but the functional and biological correlates of such alterations are unclear. If the functional connotations of structural MRI measures ...

objective: the aim of this cross-sectional analytic study was to evaluate the diagnostic efficacy of panoramic-based indices of the mandible (mental index-mi, mandibular cortical index-mci and panoramic mandibular index-pmi) and to determine their correlation with bone mineral density (bmd) of the femoral neck and lumbar vertebrae (l2-l4) in order to assess the possibility of using these parame...

accurate measurements of physical characteristics of bone are essential for diagnosis, assessment of change following treatment, and therefore, indirectly, for evaluation of new forms of therapy. this is particularly true of osteoporosis and aging skeleton, in which fractures occur easily. methods: in this study an ultrasonic system was set-up and calibrated on plexiglas tubes of variable thick...

Very preterm birth (gestational age <33 weeks) is associated with alterations in cortical thickness and with neuropsychological/behavioural impairments. Here we studied cortical thickness in very preterm born individuals and controls in mid-adolescence (mean age 15 years) and beginning of adulthood (mean age 20 years), as well as longitudinal changes between the two time points. Using univariat...

INTRODUCTION Several studies report an association between body mass index (BMI) and cortical thickness in adults. Some studies demonstrate diffuse cortical thinning in obesity, while others report effects in areas that are associated with self-regulation, such as lateral prefrontal cortex. METHODS This study used multilevel modeling of data from the NIH Pediatric MRI Data Repository, a mixed...

BACKGROUND The lateral pillar of the femoral head is an important site for disease development such as osteonecrosis of the femoral head. The femoral head consists of medial, central, and lateral pillars. This study aimed to determine the biomechanical effects of early osteonecrosis in pillars of the femoral head via a finite element (FE) analysis. METHODS A three-dimensional FE model of the ...

Online gaming addiction, as the most popular subtype of Internet addiction, had gained more and more attention from the whole world. However, the structural differences in cortical thickness of the brain between adolescents with online gaming addiction and healthy controls are not well unknown; neither was its association with the impaired cognitive control ability. High-resolution magnetic res...

Transcranial magnetic stimulation (TMS) is commonly used to examine corticospinal excitability (CSE) and related behaviors. Individual differences in brain morphology may influence responses TMS, but clarification needed. PURPOSE: To explore the relationship between cortical thickness CSE when targeted lower extremity corticomotor representation. METHODS: Twenty women (20.4 ± 1.8 yr) completed ...

In normal humans, relationships between cognitive test performance and cortical structure have received little study, in part, because of the paucity of tools for measuring cortical structure. Computational morphometric methods have recently been developed that enable the measurement of cortical thickness from MRI data, but little data exist on their reliability. We undertook this study to eval...