noise-induced hearing loss (nihl) is the most common complication of long-term noise exposure, though there  are  some  other  complications  due  to  exposure  to  noise.  metabolic  complications  of  the  noise exposure are being evaluated in recent studies. we aimed to assess the relationship between nihl and lipid profile, and fasting blood sugar (fbs). in this cross-sectional  study, 462 ...

Thirty HLA-A2 women with metastatic breast cancer received up to 14 vaccinations with MDA-MB-231-CD80, an HLA-A2 allogeneic breast cancer cell line, which had been lipofected with the cDNA for the CD80 costimulatory molecule. Tumor cells were administered with BCG or GM-CSF as an adjuvant. Sera obtained before and after vaccination were analyzed for antibodies to tumor cell lysate, MUC1, HER2/n...

Background: Chronic treatment with fetal bovine serum (FBS) causes gradual vasoconstriction, vascular wall thickening, and contractility reduction in organ-cultured vascular tissues. We have previously demonstrated that Rho-associated kinase (ROCK) inhibitors prevent the functional alterations of small arteries in response to the FBS treatment. Here, we tested a further hypothesis that the chro...

OBJECTIVE The aim was to estimate the prevalence of Insulin Resistance (IR) in Poly Cystic Ovary Syndrome (PCOS) and analyze its clinical parameters. METHODOLOGY This observational study was conducted at Dow University Hospital during June 2011 till May 2012. Patients of PCOS were selected, an anthropometric measurement, examination and fasting blood test for sugar (FBS) and insulin was perfo...

BACKGROUND Tissue regeneration and recovery in the adult body depends on self-renewal and differentiation of stem and progenitor cells. Mesenchymal stem cells (MSCs) that have the ability to differentiate into various cell types, have been isolated from the stromal fraction of virtually all tissues. However, little is known about the true identity of MSCs. MSC populations exhibit great tissue-,...

BACKGROUND No optimal methods for short-term hepatocyte preservation have been established. We have recently developed a prominent oxygen-permeable bag (Tohoku Device [TD]) for pancreatic islet culture and transplantation. In this study, we investigated whether TD is also effective for hepatocyte preservation and tried to optimize other conditions. METHODS Hepatocytes were preserved in the fo...

OBJECTIVE High blood pressure and diabetes mellitus account for over 50% of annual visits to health facilities in Trinidad and Tobago. This study investigates the ability of various absolute and relative body composition variables to predict elevated fasting blood sugar (FBS) and blood pressure (BP). SUBJECTS AND METHODS Participants had overnight fasting finger-stick blood glucose analysed w...

AIMS Intercellular interactions between cardiomyocytes (CMs) and cardiofibroblasts (FBs) are important in the physiological and pathophysiological heart. Understanding such interactions is important for developing effective heart disease therapies. However, until recently, little has been known about these interactions. We aimed to investigate structural and functional connections between CMs a...

Bleaching of polymeric materials can be achieved by blending or surface treatment with fluorescent brighteners, FBs [1]. In both cases the FB migrates with time, and the degree of whiteness decreases. The introduction of polymerizable groups into the FB makes it applicable in the copolymerization process with vinyl monomers, resulting in the formation of covalent bonds in the polymer molecule. ...