Successful treatment of human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS) with highly active antiretroviral therapy (HAART) requires that patients maintain nearly perfect adherence to the prescribed regimen. Suboptimal adherence to antiretroviral therapy is clearly the most common cause of virologic failure of HAART regimens. Given the critical role of adheren...

background: despite the effectiveness of drug therapy in diabetes management high rates of poor adherence persist. the purpose of this study was to determine the factors influencing the medication adherence and dietary regiment in type2 diabetic patients. methods: this cross sectional study was conducted on 300 type2 diabetic patients referred to general internal medicine clinic, yazd shohdaye ...

OBJECTIVE The individual components of metabolic syndrome may be independent predictors of mortality in patients with liver disease. We aimed to evaluate the prevalence of metabolic syndrome and its related components in hepatitis C virus-infected patients who are not obese and do not have type 2 diabetes. METHODS This cross-sectional study included 125 patients infected with hepatitis C viru...

Introduction The recent epidemic rise in metabolic syndrome/insulin resistance and type 2 diabetes are considered to be a result of a sedentary lifestyle combined with a high caloric diet. Earlier reports have consistently shown a link between a high fat intake, especially saturated fat, and insulin resistance [1]. More recently, the intake of simple carbohydrates, especially fructose, have bee...

The metabolic syndrome (MetS) produces low-grade inflammation, endothelial dysfunction, platelet hyperactivity, oxidative stress and ultimately contributes to cardiovascular disease (CVD) development. Fatty acids such as n-3 n-6, monounsaturated, conjugated, highly unsaturated, short-chain types, their metabolism can impact the development of MetS associated features. Furthermore, quality quant...

The present study aimed to examine the effects of the types of high-calorie diets (high-fat and high-fat-high-sucrose diets) and two different developmental stages (post-weaning and young adult) on the induction of metabolic syndrome. Male, post-weaning and adult (3- and 8-week old, respectively) Sprague Dawley rats were given control, high-fat (60% kcal), and high-fat-high-sucrose (60% kcal fa...

Background Adherence to colonoscopy recommendations can reduce colorectal cancer (CRC) morbidity and mortality. However, little is known about the use of colonoscopy among persons at risk for Lynch syndrome prior to clinical genetic testing (CGT) and how notification of mutation carrier status affects screening behaviors. The goal of this study was to evaluate colonoscopy use and attitudes towa...

BACKGROUND Depression is associated with poor adherence to medications and worse prognosis in patients with acute coronary syndrome (ACS). PURPOSE To determine whether cognitive, behavioral, and/or psychosocial vulnerabilities for depression explain the association between depression and medication adherence among ACS patients. METHODS One hundred sixty-nine ACS patients who agreed to have ...