There has been a major progress in the area of radioprotective agents since the early 1980s in terms of biological and mechanistic evaluation of the large number of naturally occurring or synthesized compounds. This information led to the development of a new generation of derivative compounds. The development of radio protective agents has been the subject of intense research in view of their ...

Fifty three patients with duodenal ulcer were treated with 40 mg of famotidine at bed time. Repeat endoscopy showed healing rates of 69.8% and 83% at 4 and 6 weeks respectively. Seven patients were kept on a maintenance dose of 20 mg nocte for one year, of these one had a relapse despite taking the drug regularly. No appreciable side effects were observed with the drug (JPMA 39:104, 1989).

Hiccups, which are caused by involuntary contractions of inspiratory muscles, can cause discomfort and when intractable, may, potentially, be a severe condition. Chronic hiccups have been treated with a variety of pharmacological agents including chlorpromazine, metaclopromide, nifedipine, haloperidol, lidocaine, baclofen and various gastric acid secretion suppressors [1–3]. This neurorespirato...

Twenty-one strains of Campylobacter pylori (Campylobacter pyloridis) were tested for susceptibility to norfloxacin and other agents by the serial agar dilution method. Ampicillin (MIC for 90% of isolates [MIC90], 0.016 micrograms/ml) and famotidine (MIC90, greater than 1,024 micrograms/ml) were, respectively, the most and the least active of the agents tested. Norfloxacin (MIC90, 1 microgram/ml...