1: Department of Pediatrics, Bureau de l’Éthique Clinique, Université de Montréa; 2: Neonatology, Clinical Ethics Unit, Palliative Care Unit, Research Center, Unité de Recherche en éthique Clinique et partenariat famille, CHU Sainte-Justine, Montreal, Quebec, Canada. 3: Parent representative 4: Human Health Therapeutics, National Research Council, Montréal, Canada 5: UCL Elizabeth Garrett Ander...

BACKGROUND Recombinant activated factor VII induces hemostasis in patients with coagulopathy disorders. AryoSeven™ as a safe Iranian Recombinant activated factor VII has been available on our market. This study was performed to establish the safety of AryoSeven on patients with coagulopathy disorder. METHODS This single-center, descriptive, cross sectional study was carried out in Thrombus an...

how to cite this article: najafi mr, najafi ma, safaei a. association of family history of epilepsy with earlier age onset of juvenile myoclonic epilepsy. iran j child neurol. spring 2016; 10(2):10-15. abstract objective juvenile myoclonic epilepsy (jme) is supposedly the most frequent subtype of idiopathic generalized epilepsies (ige). the aim of this study was to determine the prevalence of j...

background : this study aimed to compare different body mass index (bmi) categories in individuals with diabetes, prediabetes and normal glucose tolerance among the first degree relatives of type 2 diabetic patients. methods : a cross-sectional study was conducted during 2005-2007 in isfahan, iran. it evaluated 3323 first-degree relatives of diabetic patients selected by consecutive convenient ...

Sequencing the complete factor IX gene of 2 sisters with hemophilia B with different phenotypes and no family history of hemorrhagic diathesis revealed a common 5' splice site mutation in intron 3 (T6704C) in both and an additional missense mutation (I344T) in one. The presence of dysfunctional antigen in the latter strongly suggested that these mutations are in trans. Neither mutation was foun...

background: individuals with a positive family history of colorectal cancer have an increased risk of developing this type of cancer. the number of affected relatives and the age at diagnosis are two factors that increase the risk of colorectal cancer. the aim of this study was to assess the prevalence of a positive family history of colorectal cancer in a random sample among the iranian genera...

BACKGROUND Strong associations between infant vocabulary and school-age language and literacy skills would have important practical and theoretical implications: Preschool assessment of vocabulary skills could be used to identify children at risk of reading and language difficulties, and vocabulary could be viewed as a cognitive foundation for reading. However, evidence to date suggests predict...