MOTIVATION Gene regulatory elements are often predicted by seeking common sequences in the promoter regions of genes that are clustered together based on their expression profiles. We consider the problem in the opposite direction: we seek to find the genes that have similar promoter regions and determine the extent to which these genes have similar expression profiles. RESULTS We use the dat...

The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scannin...

The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scannin...

Background and Aim: Several studies have compared the orthodontists’, dentists’, and dental patients’ opinions with regard to facial profile esthetics; however, the Iranian population has been limitedly researched in this respect. Our aim was to determine the differences in the esthetic preferences of Iranian patients, dentists, and orthodontists with regard to facial profile esthetics. Materi...

Background: Dyslipidemia is considered an independent risk factor for coronary heart disease (CHD). In the present study, we examined lipid profiles and paraoxonase 1 (PON1) activity and atherogenic indexes status and the relationship of PON1 activity by high-density lipoprotein (HDL) and atherogenic indexes in CHD patients and healthy people. Methods: The aim of the study was to compare PON...

Abstract. H-modes operated at higher li with the current ramp down have shown higher energy confinement with higher density in JT-60U. The H-factor evaluated for the core plasma depends strongly on li with the relation of H89core ∝ li for the case without sawtooth activities. Center peaked profiles of electron density and electron temperature are obtained in high li H-modes. While the periphera...

     Megaloporous controlled release tablets of diclofenac sodium (DS) were prepared with two kinds of granules. One of them is the restraining-phase matrix granule (RMG) and it controls the release rate of the drug. The other one is the soluble housing-phase matrix granule (HMG) and controls liquid penetration into the system. Carnauba wax and Eudragit L 100 polymers were used to constitute th...

BACKGROUND The thrombin-generation assay has a variety of clinical uses, including diagnosis of thromboembolism-related disease, and particular profiles are associated with thrombophilic risk factors. The aim of this study was to evaluate the use of this assay in screening and identifying patients who require specific thrombophilic testing. METHODS We used a 2-step approach to perform specifi...

In this paper based on ROSAT/PSPC data we investigate the emission measure profiles of a sample of hot clusters of galaxies (kT > 3.5 keV) in order to explain the differences between observed and theoretically predicted LX–T relation. Looking at the form of the emission measure profiles as well as their normalizations we find clear indication that indeed the profiles have similar shapes once sc...