OBJECTIVE This study evaluated the efficacy and safety of a new device (Eyedrop(®)) designed for eye drop instillation in patients with and without glaucoma. METHODS This prospective study included consecutive patients with glaucoma and healthy participants. After a complete eye examination and determination of baseline intraocular pressure (IOP), topical hypotensive medication was introduced...

The current treatment of wet age-related macular degeneration (wAMD) relies on monthly intravitreal or intravenously injection vascular endothelial growth factor (VEGF) inhibitor photodynamic (PDT) agents to inhibit choroidal neovascularization. However, traumatic local therapy and exogenous long-distance fundus drug delivery often lead secondary eye damage, low efficiency, immunogenic inflamma...

Nilsson and Nivre (2009) introduced a treebased model of persons’ eye movements in reading. The individual variation between readers reportedly made application across readers impossible. While a tree-based model seems plausible for eye movements, we show that competitive results can be obtained with a linear CRF model. Increasing the inductive bias also makes learning across readers possible. ...

Intra Ocular Pressure (IOP) is the fluid pressure inside the eye and is the most important risk factor for glaucoma. From the roots of Coleus forskohlii, an aromatic herb growing all over India, we extracted Forskolin. In this study we studied the IOP lowering activity of two strengths of Ocufors, viz., Ocufors (Forskolin 1% w/v ophthalmic solution) and Ocufors (Forskolin 0.15% w/v ophthalmic s...

A 21-year-old Malay woman presented with a 4-day history of left eye progressive painful blurring of vision due to cosmetic CL wear. She had always bought her CLs from a night market and disposed it after every 3–4 months. She had a very poor CL hygiene regime and continuously wore the lenses for more than 8 hours daily. Prior to the presentation, she had been using a combination of steroid and...

Green nail syndrome (chromonychia) is a nail disorder characterized by onycholysis and green-black discoloration of the nail bed. This condition is often associated with chronic paronychia. Pseudomonas aeruginosa is the most commonly identified organism in cultures from the affected area. Despite the various treatment options available, removal of the nail is still necessary in many cases. A 35...

To determine eye drop type and usage frequency investigate risk factors for no use in individuals with symptomatic dry (DE) Japan. Crowdsourced observational study. This study was conducted using the DryEyeRhythm smartphone application between November 2016 September 2019. Data collected included of use, demographics, medical history, lifestyle, self-reported symptoms. Symptomatic DE defined as...

INTRODUCTION Travoprost 0.004%/timolol maleate 0.5% fixed combination eye drops are available in Japan. We prospectively investigated the intraocular pressure (IOP)-decreasing effect of travoprost 0.004%/timolol maleate 0.5% fixed combination eye drops and the adherence of patients to the administration protocol. MATERIALS AND METHODS We studied 43 eyes from 43 patients diagnosed with primary...

BACKGROUND The government-led "evidence-based guidelines for cataract treatment" labelled pirenoxine and glutathione eye drops, which have been regarded as the standard care for cataracts in Japan, as lacking evidence of effectiveness, causing great upset among ophthalmologists and professional ophthalmology societies. This study investigated the reasons why such "scientific evidence of treatme...