BACKGROUND Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU), is unique among human pathogens in its capacity to produce a polyketide-derived macrolide called mycolactone, making this molecule an attractive candidate target for diagnosis and disease monitoring. Whether mycolactone diffuses from ulcerated lesions in clinically accessible samples and is modulated by antibiotic ther...

10 11 Reduced bioavailability to soil microorganisms is probably the most limiting factor in the 12 bioremediation of polycyclic aromatic hydrocarbons PAH-polluted soils. We used sunflowers 13 planted in pots containing soil to determine the influence of the rhizosphere on the ability of soil 14 microbiota to reduce PAH levels. The concentration of total PAHs decreased by 93% in 90 days 15 when...

The in vitro uptake and incorporation of [H]ui idine by blastocysts of the tammar wallaby showed a 16and 30-fold increase from day 0 to day 10 after removal of pouch young, respectively. Two of the six non-expanded blastocysts recovered on day 5 showed a tenfold increase in incorporation. During the first ten days after removal of pouch young the diameter of the blastocyst increased threefold. ...

AIMS To evaluate the persistence of Mycobacterium avium subsp paratuberculosis (Myco. paratuberculosis), Salmonella enterica serotype Typhimurium (Salm.Typhimurium) and a commensal Escherichia coli (E. coli) isolate under the low pH and high organic acid (OA) conditions of ensiling of forages. METHODS AND RESULTS Decay rates and the time required to obtain a 90% reduction in cell concentratio...

Plants modify nutrient availability by releasing chemicals in the rhizosphere. This change in availability induced by roots (bioavailability) is known to improve nutrient uptake by individual plants releasing such compounds. Can this bioavailability alter plant competition for nutrients and under what conditions? To address these questions, we have developed a model of nutrient competition betw...

• The stress-related phytohormones, salicylic acid (SA) and abscisic acid (ABA), and the three jasmonates, jasmonic acid (JA), cis-12-oxo-phytodienoic acid (cis-OPDA), and (+)-7-iso-jasmonoyl-L-isoleucine (JA-Ile), were investigated in phloem and xylem exudates of Cucurbita maxima. • Phloem and xylem exudates were separately collected and analysed via liquid chromatography-mass spectrometry. • ...

Soluble root exudates collected from the barley grown in Fe deficient-nutrition solutions were added to soil to study their effects on metal solubility. The results showed that the addition of barley root exudates from the Fe deficient-nutrition solutions resulted in a 4.7-, 3.2-, 9.7-, 4.9and 11.5-fold increase in the concentrations of soluble Cu, Pb, Zn, Cd and Fe, respectively, in comparison...

Copepods are ubiquitous in aquatic habitats. They exude bioactive compounds that mediate mate finding or induce defensive traits in prey organisms. However, little is known about the chemical nature of the copepod exometabolome that contributes to the chemical landscape in pelagic habitats. Here we describe the development of a closed loop solid phase extraction setup that allows for extraction...

Diabetic retinopathy (DR) and age related macular degeneration (ARMD) are among the major causes of visual impairment all over the world. DR is mainly characterized by small red spots, namely microaneurysms and bright lesions, specifically exudates. However, ARMD is mainly identified by tiny yellow or white deposits called drusen. Since exudates might be the only visible signs of the early diab...

OBJECTIVE The aim of this study was to identify the participation of the coagulation system in the differential diagnosis of pleural effusions. INTRODUCTION Imbalance between immunologic and metabolic factors triggers a sequence of events resulting in pleural reactions and accumulation of fluid. The coagulation system, which is fundamental for the maintenance of homeostasis, contributes to th...