BACKGROUND Tuberculosis (TB) is associated with oxidative stress and the induction of host anti-oxidants to counteract this response. Heme oxygenase-1 (HO-1) is a critical promoter of cytoprotection in diverse disease models including mycobacterial infection. Nevertheless, the pattern of expression of HO-1 in human tuberculosis has not been studied. Here, we examine expression of HO-1 in M. tub...

Background and objective There are no recent data on the prevalence of drug-resistant tuberculosis (DR TB) in Cambodia. We aim to describe TB drug resistance amongst adults with pulmonary and extra-pulmonary TB and human immunodeficiency virus (HIV) co-infection in a national referral hospital in Phnom Penh, Cambodia. Design Between 22 November 2007 and 30 November 2009, clinical specimens from...

The present study was conducted to find out the ethambutol resistance pattern of indigenous isolates of Mycobacterium tuberculosis from Tuberculosis diagnosed human patients. A total of 172 specimens were collected from six different sources and comprised of 84.9% sputum, 10.5% pus and 4.7% bronchial washings. There were 70.9% males and 29.1% females with 84.30% pulmonary and 15.69% extra-pulmo...

the study was aimed to investigate the diagnostic differences between male and female patients in pulmonary tuberculosis in a tertiary 660 bedded educational respiratory medicine hospital, istanbul, turkey. a retrospective study was conducted with the new diagnosed, 50 men and 50 female pulmonary tuberculous patients. age, symptoms, personal history, radiologic and sputum smear findings were co...

background: tuberculosis of the larynx is a rare form of tuberculosis. patients usually present with hoarseness or dysphagia and other nonspecific constitutional symptoms like fever or localized pain. in this study, we present a case of primary vocal cord lesion with tuberculosis. case presentation: a 72 year old man presented with hoarseness of voice, low grade fever, and night sweating with i...

Although pulmonary tuberculosis is known to be the most common type in tuberculosis, it actually can affect any organ system. However, abdominal type is very rare among the extra-pulmonary types, and obstructive jaundice caused by lymphadenopathies due to tuberculosis is especially uncommon manifestation even in endemic areas. Tuberculous lymphadenopathies can mimic lymphadenopathies by other m...

We conducted this study to assess the efficacy of intermittent short course therapy in all forms of pediatric tuberculosis using a coordinated approach with Revised National Tuberculosis Control Programme (RNTCP). Sixty five children were treated using RNTCP protocols with some modifications, such as dose adjustments or prolongation of treatment in selected children. Overall response rate was 9...

Introduction: Increased occurrence of tuberculosis in diabetic population is known since long time. Tuberculosis (TB) remains one the world’s deadliest communicable diseases and India currently bears highest burden World. Diabetes mellitus (DM) becoming epidemic 21st century with having second largest populationglobally. This emphasizes importance investigating association diabetes mellitus.Aim...