introduction: septic shock is now recognized to be associated with multiple critical organ failure, usually attributable to the uncontrolled release of multiple pro-inflammatory cytokines such as tnf, inf, il-6, il-1, and no (nitric oxide). no is one of the most important proinflammatory mediators in sepsis and septic shock. it is a potent vasodilator, and appears to be responsible for hypotens...
