ABSTRACT Ischaemic reperfusion (IR) injury is a major cause of graft loss, morbidity and mortality following orthotopic liver transplantation (OLT). Demand for liver transplantation has resulted in increasing use of marginal grafts that are more prone to IR injury. Remote ischaemic preconditioning (RIPC) reduces IR injury in experimental models, but recipient RIPC has not been evaluated clinica...

To investigate the effects of supplemental oxygen on cardiac rhythm during gastroscopy, 103 patients aged over 60 were randomised to receive either supplemental oxygen or air at 2 litres/minute during the procedure. Pulse rate, blood pressure, oxygen saturation, and a Holter cardiac trace were monitored before, during, and for one hour after the gastroscopy. A wide range of electrocardiographic...

The study of depth-averaged currents is great significance for the application underwater gliders. In order to solve problem low prediction accuracy time series-based current method, factors affecting are analyzed and a data-driven method an glider with sailing parameters proposed in this paper. First, glider’s historical profile period navigation taken as inputs construct multi-input double-ou...

In patients with dementia associated with Parkinson's disease (PD), the efficacy and safety of rivastigmine, an inhibitor of acetylcholinesterase and butyrylcholinesterase, were previously demonstrated in a 24-week double-blind placebo-controlled trial. Our objective was to determine whether benefits were sustained over the long term. Following the double-blind trial, all patients were permitte...

INTRODUCTION The concentration of noradrenalin and corticosterone as the two nociception modulators change after fasting or stress situation. The aim of present study was to investigate the effect of food deprivation on formalin-induced nociceptive behaviours and plasma levels of noradrenalin and corticosterone in rats. METHODS Food was withdrawn 12, 24 and 48 h prior to performing the formal...

the aim of this study was to evaluate the effects of atorvastatin on negative symptoms in patients with chronic schizophrenia. the study was a prospective, double-blind, 6-week trial. forty patients participated in the study; 19 patients were assigned to the atorvastatin group as well as 21 patients to the placebo group. for assessing negative signs, we used scale for the assessment of negative...

Background: Gamma-amino butyric acid (GABA) agonists have been effective in the treatment of withdrawal from benzodiazepines, sedatives and alcohol, and reducing the craving for cocaine. Valproate is a GABAergic drug effective in the treatment of neuropathic pain and also in withdrawal from benzodiaepines, sedatives, and alcohol. The purpose of this double-blind trial was to evaluate the ef...