Objective: The current study was planned to evaluate the antiasthamatic effect of Electrohomeopathic medicine Pettorale in various experimental models.
 Methods: antiasthmatic activity studied on different animals like histamine induced bronchospasm guinea pig, haloperidol catalepsy rats, egg albumin paw anaphylaxis rats and milk leukocytosis mice.
 Conclusion: Preliminary phytochemic...

OBJECTIVE This study was designed to demonstrate that four weeks of fluticasone propionate (FP) 100 micrograms (mcg) combined with salmeterol 50 mcg twice daily (BID) via DISKUS(®) resulted in protection against bronchospasm induced by activity, as measured by standardized exercise challenge testing in pediatric and adolescent subjects who required regular use of inhaled corticosteroids for the...

UNLABELLED We conducted this study to determine the risk factors for the development of bronchospasm after the administration of rapacuronium and to determine if children with bronchospasm on induction of anesthesia were more likely to have received rapacuronium compared with other muscle relaxants. In a retrospective cohort study, all anesthetic records in which rapacuronium was administered w...

BACKGROUND Changes in airway mucosal osmolarity are an underlying mechanism of bronchoconstrictive responses to exercise and hypertonic saline (HS). The purpose of this study was to examine whether an osmotic challenge test using HS can predict exercise-induced bronchospasm (EIB) in asthma patients. METHODS Thirty-six young male asthmatic patients underwent bronchial challenge tests based on ...

We evaluated the airway activity of the novel phosphodiesterase type 4 inhibitor SB 207499 [Ariflo; c-4-cyano-4-(3-cyclopentyloxy-4-methoxyp henyl-r-1-cyclohexane carboxylic acid)], in the guinea pig. Ovalbumin (OA)-induced contractions of guinea pig isolated tracheal strips were inhibited by SB 207499 with an EC50 of 1 microM but had little or no effect on exogenous agonist-induced contraction...

IN the perioperative period, anaphylactic reactions are often induced by the intravenous administration of muscle relaxants, antibiotics, colloids, and radiocontrast materials as well as after local contact with latexcontaining materials (e.g., gloves, catheters, airway tube) and chlorhexidine. Inhalation of toxic and highly irritant substances contained in cleaning solutions has occasionally b...

The aim of the present study was to evaluate invitro and invivo antiasthmatic activity of ethanolic bark extract of Symplocos racemosa. For invitro study, isolated guinea pig ileum was used and dose response curve of histamine in plain Tyrode solution and in Tyrode solution containing 25 μg/ml ethanolic barks extract of Symplocos racemosa were performed. For invivo study histamine induced bronc...

PURPOSE Leukotriene receptor antagonists (LTRAs) are used to treat aspirin-intolerant asthma (AIA); however, the protective effects of long-term LTRA administration against aspirin-induced bronchospasm have not been evaluated. OBJECTIVES We investigated the efficacy of a 12-week treatment with a LTRA in protecting against aspirin-induced asthma in AIA patients. METHODS Fifty-two adult patie...

Bronchospasm is an anesthetic emergency that can lead to disastrous outcomes if treatment is irresolvable. An anesthesia provider must immediately initiate treatment if bronchospasm is suspected in order to avoid negative sequelae. The following is a case report of a 32-year-old man who experienced refractory bronchospasm upon emergence from general anesthesia. This article discusses the initia...