We wish to thank our neurosurgical colleagues Mr. P. Harris, Mr. J. F. Shaw, and Mr. G. N. N. Reddy; and also Professor Sir John Bruce and Dr. A. Brownfie Smith for their help with some general surgical and otorhinolaryigological aspects respectively of Case 5. We are particularly grateful to Dr. A. S. Brown, consultant anaesthetist, and Dr. A. A. Donaldson, consultant radiologist, for their sk...

Phototherapy was developed in the late 1950s and is today considered the mainstay of managing neonatal jaundice. Yet prominent academic leaders continued to promote the older approach of exchange transfusion well into the 1970s, despite the considerable risks involved. This article explores why phototherapy took so long to be embraced, and how pediatric residents were caught in the middle of th...

OBJECTIVE To determine the role of intravenous administration of human albumin prior to blood exchange in term neonates for reduction of total serum bilirubin (TSB). DESIGN Randomized controlled trial. SETTING Neonatal Unit of Nemazee Hospital, affiliated with Shiraz University of Medical Sciences, southern Iran. PATIENTS Fifty out-born term neonates with gestation age <37 weeks, birth we...

Transcutaneous bilirubin (TcB) has the potential to reduce total serum bilirubin (TS) sampling. The principal aim of this study was to determine and compare the number of initial TSB samples (TSBs) in two postnatal units (hospitals A & B) whereby hospital A used TcB and hospital B did not. A secondary aim was to determine the clinical factors that led to initial TSBs exceeding exchange transfus...

A 5-year-old female with SCD presented thunderclap headaches, followed by stabbing headaches after receiving an exchange transfusion and prednisolone. She developed ischemic infarcts in the left parietal right paramedian frontal lobes.