A template-directed synthetic approach to halogen-bridged mixed-valence platinum complexes has been performed in organic media using, for instance, a synthetic peptide bearing two bis(ethylenediamine)-based Pt(IV) complexes with two axial bromide anionic ligands, [(Pt(IV)Br2(en))2](RSO3)4, and a [Pt(II)(en)2](RSO3)2 complex (R = (C12H25OCH2)2CHO(CH2)3-).

The first derivative of carboxypeptidase A, cobalt(III)(ethylenediamine-N,N’-diacetato)(arsanilazotyrosinato 248 (Co(III)(EDDA)(AA-CPA-Zn)), in which only the active site residue tyrosine 248 is blocked, has been shown to be completely peptidase-inactive while retaining esterase activity. Peptides are excellent inhibitors of esterase activity showing Ki values somewhat below the corresponding K...

The preparation of bis-thiazolidinones has been achieved by a one-pot condensation reaction of araldehydes, ethylenediamine and thioglycolic acid in the presence of nano-CuCr2O4 nanoparticles under reflux conditions in toluene. This method provides several advantages including easy workup, excellent yields, short reaction times, reusability of the catalyst and low catalyst loading.

The reaction of [Pt(en)(H(2)O)(2)](2+) with 1 equivalent of 1-methylcytosine at an initial pH of 6 ultimately led to the 1-methylcytosinato-bridged (ethylenediamine)platinum(II) dimer, [(en)Pt(MetCyt-H)(2)Pt(en)](NO(3))(2) (1). The species during the reactions prior to formation of 1 have been investigated by using (195)Pt NMR spectroscopy. From the reaction mixture the [Pt(en)(MetCyt)(2)](NO(3...

Titanium dioxide (TiO2) nanotubes (TNT) were successfully synthesized using different N-containing ligands via hydrothermal method. Methylamine, ethylenediamine and diethylenetriamine with Ti/ligand molar ratios (1:1, 1:3, 1:5 1:8) prepared. As-synthesized TiO2 without also prepared for comparison purpose. The X-Ray Diffraction patterns confirmed the presence of anatase phase in all samples whe...

In the title compound, C(4)H(14)N(2) (2+)·2C(7)H(5)O(3) (-), both the N,N-dimethyl-ethylenediamine N atoms are protonated and two 3-hy-droxy-benzoate anions act as counter-ions. In the crystal, anions and cations are linked by a network of N-H⋯O and O-H⋯O hydrogen bonds.

The structure of histargin, an inhibitor of carboxypeptidase B, produced by Streptomyces roseoviridis MF118-A5 strain, has been defined as N-[(S)-1-carboxy-4-guanidinobutyl]-N'-[(S)-1-carboxy-2-(imidazol-4 -yl) ethyl]ethylenediamine, by spectral analysis and chemical synthesis.

The mechanism of water reduction catalysed by a mononuclear copper complex Cu(bztpen) (bztpen = N-benzyl-N,N',N'-tris(pyridine-2-ylmethyl)ethylenediamine) has been elucidated by DFT calculations, revealing that hydrogen evolution proceeds via coupling of a Cu(ii)-hydride and a pendant pyridinium, and providing important implications for the future design of new catalytic systems for water reduc...

DNA microarrays were used to probe the transcriptional response of Escherichia coli to N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). Fifty-five transcripts were significantly up-regulated, including all of the genes that are regulated by Zur and many that are regulated by Fur. In the same TPEN-treated cells, 46 transcripts were significantly down-regulated.

Herein we demonstrate the use of ethylenediamine bisborane (EDAB) as a suitable hydrogen source for transfer hydrogenation reactions on C-C double bonds mediated by metal nanoparticles. Moreover, EDAB also acts as a reducing agent for carbonyl functionalities in water under metal-free conditions.