Background: Enhancing the industrial yeast strains ethyl acetate yield through a precise and seamless genetic manipulation strategy without any extraneous DNA sequences is an essential requisite and significant demand. Objectives: For increasing the ethyl acetate yield of industrial brewer’s yeast strain, all the ATF1 alleles were overexpressed t...

BACKGROUND Alzheimer's disease (AD) is a progressive neurodegenerative disorder clinically characterized by loss of memory and cognition. The effective therapeutic options for AD are limited and thus there is a demand for new drugs. Aegle marmelos (Linn.) (A. marmelos) leaves have been used in traditional medicine to promote intellect and enhance memory. In this study, we evaluated A. marmelos ...

Sauromatum giganteum (Engl.) Cusimano & Hett Tuber are used in Chinese folklore medicine for treatment of neoplasms. However, the claim has not been scientifically validated. The aim of the study is to screen the antitumor bioactive fraction of Sauromatum giganteum (Engl.) Cusimano & Hett Tuber and sensitive tumor cell lines using a cytotoxicity assay in vitro and tumor transplantation ...

The stem bark of Carallia brachiata was studied for wound healing activity. The bark was extracted with petroleum ether, ethyl acetate and methanol successively. All the extracts were screened for wound healing activity by excision and incision models in Wistar rats. The ethyl acetate and methanol extracts were found to possess significant wound healing activity. The extracts revealed the prese...

Present study was done to assess the in vitro antiarthritic activity of the plant Sphaeranthus amaranthoides Burm F (Asteracea). Four different extract of increasing polarity namely petroleum ether, chloroform, ethyl acetate and methanol were prepared. Antiarthritic potential of the plant was assessed by two methods namely, effect on protein denaturating and effect on membrane stabilization. Th...

The reaction of alkaline 2,4-dihydroxyquinoline 1 and 1-tetralone 2 in 2% sodium hydrox­ ide solution with vinyl acetate afforded a brown solid 3, which on treatment with phospho­ rous oxychloride yielded 2,4-dichloro-3-[l’-(l-chloro-naphth-2-yl)ethyl]quinoline (4). The same reaction of 1 and chromanone 7 with vinyl acetate afforded 2,4-dichloro-3-[l’-(4-chloro2-methyl-chromen-3-yl)ethyl]quinol...

growing interest to use natural preservatives and spices with antimicrobial effects and large amounts of floral bio-residues (92.6 g per 100 g) generated and wasted in the production of saffron spice guided this study  to evaluate  the opportunity to expand the uses of c. sativus flowers (petals and stamens), beyond the spice (dried stigmas). the antibacterial potential of total extracts and di...

background and objectives: malaria is a remarkable cause of death in the world. several ways are used by researchers to control or to decrease the detrimental effects of the disease, in which natural insecticides with less malaria vectors resistance and lower environmental damages are considered in last decades.the objective of this study was to assess the larvicidal activity of the whole flowe...

fruits, leaves and tuberous roots of momordicia diocia are used in india as a folk remedy for treatment of a wide range of disorders. the objective of this study was to evaluate the hepatprotective activity of the fruits of momordicia diocia by preparing different extracts and the resultant extract were screened for the hepatprotective activity. the ethyl acetate and ethanolic extracts of momor...