OBJECTIVE To determine the potential antiulcer activity of methanol extract of Melastoma malabathricum leaves (MEMM) using various established rat models. MATERIALS AND METHODS Ten groups of rats were used and orally administered 10% DMSO (negative control), 100 mg/kg ranitidine (positive control) or MEMM (50, 250 and 500 mg/kg) followed by gastric ulcer induction either using ethanol or indo...

We examined the therapeutic effect of an ethanol extract derived from Boehmeria nivea (Linn.) Gaudich in a mouse model of experimental colitis. Treatment with 70% ethanol extract derived from B. nivea (EBN) at a dose of 100, 200, or 500 mg/(kg · d) improved colon shortening, body weight, the disease activity index (DAI), and histopathological score of DSS-induced colitis mice. DSS significantly...

The antiulcer activity of cacao liquor water-soluble crude polyphenols (CWSP) was examined. CWSP, alpha-tocopherol, sucralfate (500 mg/kg), and cimetidine (250 mg/kg) were orally administered to male SD rats 30 minutes before ethanol treatment. 5 ml/kg of ethanol given intragastrically caused lesions in mucosa of the glandular stomach. CWSP caused a reduction of such hemorrhagic lesions as well...

Membrane processes for surface water treatment include microfiltration (MF), ultrafiltration (UF) and nanofiltration (NF), depending on the target material to be removed and the limiting process economics. MF will remove turbidity, but no dissolved compounds, unless associated with colloids, UF will, depending on the molecular weight cut off (MWCO), partially remove NOM, and NF will remove NOM ...

In recent years, the effects of heterogeneous catalysts for the oxidation of organic and inorganic pollutants in industrial wastewaters are spread. Traditionally, these reactions are usually carried out using suspensions of photo-catalysts such as TiO2. A chemical method including TiCl4, Al(NO3)3, ethanol amine, ethyl acetoacetate and aqueous ammonia were used for the fabrication of TiO2-Al2O3 ...

The acetone (AEAC) and aqueous extracts (AQEAC) of Adina cordifolia, belonging to the family Rubiaceae, were studied for hepatoprotective activity against Wister rats with liver damage induced by ethanol. It was found that AEAC and AQEAC, at a dose of 500 mg/kg body weight exhibited hepatoprotective effect by lowering the Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetat...

BACKGROUND The leaves of Dissotis rotundifolia are used ethnomedically across Africa without scientific basis or safety concerns. Determination of its phytochemical constituents, antimicrobial activity, effects on the gastrointestinal tract (GIT) as well as toxicological profile will provide supportive scientific evidence in favour of its continous usage. METHOD Chemical and chromatographic t...