Practolol, propranolol, and placebo have been tested on an objective test of lithium induced tremor. Both beta-blocking agents produced significantly more tremor than the placebo. It is argued that lithium induced tremor is closer to essential than to physiological tremor.

The present appraisal indicates that blood pressure patterns in adolescence differ from those in adulthood and that the design of hypertension detection programs needs to be modified for this age group. Routine blood pressure screening within the school system would appear to be the most effective means for early detection of hypertension. Links with established hypertension clinics, preferably...

The relationship between plasma propranolol concentration and relief of essential tremor was examined in 11 patients during treatment with oral racemic propranolol in doses of 30 to 640 mg/day. Although propranolol decreased tremor in all 11 patients, the degree of improvement varied widely in individuals (mean 51%, range 25--90%), and was not related directly occurred at plasma propranolol con...

The "knockout-rate" prediction holds that essential genes should be more evolutionarily conserved than are nonessential genes. This is because negative (purifying) selection acting on essential genes is expected to be more stringent than that for nonessential genes, which are more functionally dispensable and/or redundant. However, a recent survey of evolutionary distances between Saccharomyces...

Estimating the functional topology of a network from multivariate observations is an important task in nonlinear dynamics. We introduce the nonparametric partial directed coherence that allows disentanglement of direct and indirect connections and their directions. We illustrate the performance of the nonparametric partial directed coherence by means of a simulation with data from synchronized ...

The phenotypic state of the cell is commonly thought to be determined by the set of expressed genes. However, given the apparent complexity of genetic networks, it remains open what processes stabilize a particular phenotypic state. Moreover, it is not clear how unique is the mapping between the vector of expressed genes and the cell's phenotypic state. To gain insight on these issues, we study...

The volatile leaf essential compositions of all 17 serrate leaf margin species of Juniperus (sect. Sabina) of the western hemisphere are reported and compared: J. angosturana, J. ashei, J. californica, J. coahuilensis, J. comitana, J. deppeana, J. durangensis, J. flaccida, J. gamboana, J. jaliscana, J. monosperma, J. monticola, J. osteosperma, J. occidentalis, J. pinchotii, J. saltillensis, and...

In this paper we present a statistical method for estimating the relative geometry between two images and give useful methods to characterise motion estimation error. We argue that the estimation of the camera motion should be done in a statistical framework and describe a solution for the case of calibrated images. Statistical bootstrap is used to compute the underlying probability structure o...