In order to find the correlation between the severity of carditis in acute rheumatic fever (ARF) and the erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and anti-streptolysin O (ASO) titers, we performed a retrospective study in Shiraz on one-hundred and four patients. The mean age of the patients was 11 years. Fever was seen in 85.5%, arthralgia in 95.2%, arthritis in 81.7%, car...

There is evidence showing that increased levels of oxidative stress and C-reactive protein (CRP) might be associated with obesity, hypertension, atherosclerosis and other cardiovascular diseases. This study was undertaken to investigate possible relationships among plasma 8-iso-prostaglandin F2α (8-iso-PG F2α: an index of oxidative stress), high-sensitivity (hs)CRP and membrane fluidity (a reci...

Serum adenosine deaminase (ADA) has been previously proposed to predict disease activity in patients with rheumatoid arthritis (RA). The aim of this study was to investigate the level of serum ADA, and the relationship between ADA and disease activity markers, in a group of patients with RA. A hundred and 10 patients with a diagnosis of RA were recruited from outpatient clinic of Rheumatology U...

OBJECTIVE To validate and compare the definition of the Disease Activity Score 28 based on C-reactive protein (DAS28 (CRP)) to the definition based on erythrocyte sedimentation rate (ESR). METHODS Data were analysed from two randomised, double-blind, placebo-controlled trials of abatacept of 6-month and 12-month duration in patients with rheumatoid arthritis. European League Against Rheumatis...

BACKGROUND As an irreversible disease, a treatment delay can negatively affect treatment response in rheumatoid arthritis (RA). Ultrasound and MRI have played an important role in assessing disease progression and response to treatment in RA for many years. The present study was designed to compare the diagnostic efficacy of ultrasound grading and MRI in early RA. METHODS In this retrospectiv...

BACKGROUND The mean platelet volume (MPV) reflects the size of platelets. It has been shown to be inversely correlated with level of the inflammation in some chronic inflammatory diseases. This prospective study aims to show the usability of MPV as an inflammation marker in patients with active pulmonary tuberculosis (PTB) by comparison with healthy controls. In addition, its relationships with...

BACKGROUND The differentiation of infected diabetic foot ulcers (IDFU) from non infected diabetic foot ulcers (NIDFU) is a challenging issue for clinicians. OBJECTIVES Recently, procalcitonin (PCT) was introduced as a remarkable inflammatory marker. We aimed to evaluate the accuracy of PCT in comparison to other inflammatory markers for distinguishing IDFU from NIDFU. MATERIALS AND METHODS ...

Background: Urinary tract infections (UTIs) are very common in children. Several biomarkers have been used for the diagnosis of UTI and prediction renal parenchymal involvement. Objectives: This study aimed to evaluate plasma D-dimer as a diagnostic marker Methods: cross-sectional included 41 children aged 1 month 14 years with their first febrile confirmed by positive urine culture referred Ba...

ةـصلاخلا : يوتحت لا و ةضفخنملا ةقاطلا تاذ تادحولا نم ديدعلا ىلع ةيكلسلالا تارعشتسملا ةكبش ةلصوب ةدوزم سلا ةيكل ثيح ، اهنيب اميف لاصتلال إ نكمي تارعشتسملا كلت ن دختسا ا اهم تا قيبطتلا نم د يدعلا يف . م ت د قو ا هتبقارم دار ملا ة قطنملا ى لع يئاوشع لكشب تارعشتسملا عيزوت ثحبلا اذه يف ا م لكش ب اهميس قت و إ ى ل ةدحاو لآ يوتحت ثيح ،ةقرفتم تانايب دعاوقآ لمعتل تاعومجم ة يناكم تا نايب ى لع تارعش تسمل...

Background: Inflammatory bowel disease (IBD) involves chronic inflammation of the digestive tract. In the past decades, fecal calprotectin has been proposed as a useful biomarker for the differential diagnosis between IBD patients and healthy controls. We designed this study to evaluate the diagnostic ability of fecal calprotectin (FC) and conventional inflammatory markers in IBD patients. M...