نتایج جستجو برای: esophageal reflux disease

تعداد نتایج: 1529978  

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2014
Christopher Welsh Moshe Yair Kasirer Jingyi Pan Yulia Shifrin Jaques Belik

Proton pump inhibitors reduce gastric acid secretion and are commonly utilized in the management of gastroesophageal reflux disease across all ages. Yet a decrease in lower esophageal sphincter tone has been reported in vitro in rats through an unknown mechanism; however, their effect on the gastroesophageal muscle tone early in life was never studied. Hypothesizing that proton pump inhibitors ...

Journal: :RMŽ. Medicinskoe obozrenie 2022

Gastroesophageal reflux disease (GERD) is one of the most common reasons for referral to a physician. reflux-associated extraesophageal symptoms occur in every third patient with GERD. Diagnostic difficulties and prescription effective treatment rapid resolve GERD are still important issues when managing these patients. This paper summarizes data on prevalence pattern symptoms, as well efficacy...

Journal: :Arquivos de gastroenterologia 2011
Gerson Ricardo de Souza Domingues Joaquim Prado P Moraes-Filho Aline Gonçalves Leite Domingues

CONTEXT Gastroesophageal reflux disease is one of the most common digestive diseases and an important cause of distress to patients. Diagnosis of this condition can require ambulatory pH monitoring. OBJECTIVES To determine the diagnostic yield of a wireless ambulatory pH monitoring system of 48-hours, recording to diagnose daily variability of abnormal esophageal acid exposure and its symptom...

2014
Bruno ZILBERSTEIN Juliana Abbud FERREIRA Marnay Helbo de CARVALHO Cely BUSSONS Arthur Sérgio SILVEIRA-FILHO Henrique JOAQUIM Fernando RAMOS

The gastroesophageal reflux disease is chronic and common condition that affects about 10% of the population in general22 and corresponds to about 75% of esophageal disorders, with a progressive increase in incidence over the years18. Surgical treatment is permanent, in most cases, since the fundoplication restores the competence of the lower esophageal sphincter and the hiatoplasty reduces and...

2010
Hiroto Miwa Takashi Kondo Tadayuki Oshima Hirokazu Fukui Toshihiko Tomita Jiro Watari

Noxious stimuli in the esophagus activate nociceptive receptors on esophageal mucosa, such as transient receptor potential, acid-sensing ion channel and the P2X family, a family of ligand-gated ion channels responsive to ATP, and this generates signals that are transmitted to the central nervous system via either spinal nerves or vagal nerves, resulting in esophageal sensation. Among the noxiou...

2014
Hyojin Park

Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease affecting both children and adults. The condition is characterized by an eosinophilic infiltration of the esophageal epithelium. Symptoms of esophageal dysfunction include dysphagia, food impaction and symptoms mimicking gastroesophageal reflux disease. Endoscopic examination typically reveals mucosal fragil...

Journal: :Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2004
L Dobrek M Nowakowski M Mazur R M Herman P J Thor

Gastro-esophageal reflux disease (GERD) is the result of the acid contents regurgitation back from the stomach into the esophagus. According to the endoscopic findings, GERD can be divided into two main forms: non-erosive (NERD) and erosive reflux esophagitis. The pathogenesis of GERD is associated with the impaired function of the antireflux barrier. Disturbances of the autonomic nervous syste...

2013
Maria Giacchino Vincenzo Savarino Edoardo Savarino

Non-erosive reflux disease (NERD) and functional heartburn (FH) are two different clinical entities and the clear distinction between the two forms is actually possible thanks to the use of impedance-pH monitoring. NERD is the more common manifestation of gastro-esophageal reflux disease (GERD), one of the most widespread chronic gastrointestinal disorders in Western countries. The absence of v...

Journal: :Revista do Instituto de Medicina Tropical de Sao Paulo 2010
Carlos A R Pantanali Fernando A M Herbella Maria A C A Henry Jose L B Aquino Jose Francisco Mattos Farah Jose C Del Grande

Chagas disease (CD) is very prevalent in South America, with wellknown manifestations in the digestive system. CD esophagopathy leads to a clinical and manometric picture similar to idiopathic (primary) achalasia. Although the treatment for CD esophagopathy is well established, South American surgeons and gastroenterologists are sometimes faced with CD patients without esophageal involvement bu...

Journal: :Annals of Surgery 1971

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