Biomaterial-centered infection is a dreaded complication associated with the use of biomedical implants. In this paper, the antimicrobial activity of silicone rubber with a covalently coupled 3-(trimethoxysilyl)-propyldimethyloctadecylammonium chloride (QAS) coating was studied in vitro and in vivo. Gram-positive Staphylococcus aureus ATCC 12600, Staphylococcus epidermidis HBH, 102, and Gram-ne...

Cecropin P1 was first identified as a mammalian antimicrobial peptide isolated from the pig intestine. Much research aimed at characterizing this peptide has been reported. Recently, the workers who discovered the peptide corrected their original conclusion, and confirmed that this peptide originates in fact from the pig intestinal parasitic nematode, Ascaris suum. In the present study, we carr...

OBJECTIVES Recurrent caries was partly ascribed to lack of antibacterial properties in composite resin. Silver and zinc nanoparticles are considered to be broad-spectrum antibacterial agents. The aim of the present study was to evaluate the antibacterial properties of composite resins containing 1% silver and zinc-oxide nanoparticles on Streptococcus mutans and Lactobacillus. MATERIALS AND ME...

Low solubility of proteins overexpressed in E. coli is a frequent problem in high-throughput structural genomics. To improve solubility of proteins from mesophilic Shewanella oneidensis MR-1 and thermophilic Clostridium thermocellum JW20, an approach was attempted that included a fusion of the target protein to a maltose-binding protein (MBP) and a decrease of induction temperature. The MBP was...

Objectives Periodontal diseases are one of the common oral diseases and microbial oral flora is one major factor responsible for it. Elimination of periodontal pathogens is particularly important in managing the periodontal state. This study aimed to assess the antibacterial effects of Nanosil, chlorhexidine (CHX) and probiotic mouthwashes on periodontal pathogens. Methods In this in-vitro stu...

Amaç: Artan bakteriyel enfeksiyonlar ve antimikrobiyal direnç (AMD) halk sağlığını tehdit etmektedir. Bu sorunun yönetiminde sürveyans çalışmaları büyük önem taşımaktadır. çalışmada, çeşitli örneklerden izole edilen bakterilerin tür dağılımı antibiyotik duyarlılıklarının belirlenmesi amaçlanmıştır. Yöntem: Mart 2018- 2021 tarihleri arasında … Hastanesi Tıbbi Mikrobiyoloji Laboratuvarı’na gönder...

Over the years, the use of plastics has complicated the problem of disposal of solid wastes. One strategy to reduce plastic waste is the use of biodegradable plastics. A group of these plastics are polyhydroxyalkanoates (PHAs). To date more than 250 different microorganisms are known to synthesize and accumulate PHA. Most Pseudomonas strains are able to accumulate mcl-PHA. In previous studies, ...

In recent years, valuable experience and insights have been gained into L-forms (cell-wall-deficient variants) of bacteria fungi their disease-trigger potential in cases with chronic infections, autism spectrum disorders, autoimmune neurodegenerative diseases. Based on the concept “internal” blood microbiota, consisting its relevance to health disease, current study aims outline profile dysbiot...